Establishing a framework of measurement for use in Long COVID research and practice: protocol for a scoping review involving evidence review and consultation.

Introduction: Our aim is to develop a Framework of Measurement for people living with Long COVID and their caregivers for use in Long COVID research and clinical practice. Specifically, we will characterise evidence pertaining to outcome measurement and identify implementation considerations for use of outcome measures among adults and children living with Long COVID and their caregivers.

Methods And Analysis: We will conduct a scoping study involving: (1) an evidence review and (2) a two-phased consultation, using methodological steps outlined by the Arksey and O'Malley Framework and Joanna Briggs Institute.

N95 masks increase brain blood velocity and parasympathetic outflow, yet worsen orthostatic symptoms in a healthy cohort.

Mask wearing became commonplace in everyday life during the COVID-19 pandemic and masks are frequently used in certain professions. Masks can increase end-tidal CO and the cerebrovasculature is known to vasodilate in response to hypercapnia. Orthostatic intolerance (OI) is the inability to tolerate postural transitions due to the displacement of blood volume away from the cerebral circulation, and we hypothesized that wearing a mask would improve OI symptoms by increasing brain blood flow.

Associations between age at natural menopause and risk of hypothyroidism among postmenopausal women from the Canadian Longitudinal Study on Aging (CLSA).

Menopause is a key period in women's lives associated with major physiological changes. Early menopausal age has been linked to a range of adverse outcomes. Estrogen has been found to increase levels of thyroid binding proteins in the blood; however, its effect on hypothyroidism is not well investigated.

A cohort study on the associations between age at natural menopause and rheumatoid arthritis in postmenopausal women from the Canadian Longitudinal Study on Aging.

Menopause represents a significant phase in a woman's life, marked by profound physiological changes. An early onset of menopause has been associated with a variety of negative outcomes. Estrogen has been shown to be protective of bone and joint health.

Women, orthostatic tolerance, and POTS: a narrative review.

Young women experience orthostatic intolerance to a greater degree than men. Numerous physiological pathways could be responsible for this intolerance in both healthy and pathophysiological conditions. This review discusses sex differences in hemodynamics, ventilation, autonomic control, and cerebral blood flow.