Publications by authors named "Gyu-Rim Lee"
Article Synopsis
- The combined use of alcohol and cocaine leads to more significant and unpredictable liver, heart, and brain damage compared to using either substance alone.
- Research involving marmosets and mice demonstrated that using both substances together caused worse liver injury and inflammation than individual use did.
- The study identifies hippuric acid as a critical metabolite linked to increased liver damage through inflammation pathways, suggesting that targeting the HA-STING-TNFR1 signaling axis could be a promising treatment for alcohol- and cocaine-related liver injuries.
Nonalcoholic fatty liver disease (NAFLD) is becoming one of the most common chronic liver diseases in the world. One of the features of NAFLD is hepatic fat accumulation, which further causes hepatic steatosis, fibrosis, and inflammation. Saponins, the major pharmacologically active ingredients isolated from , contain several ginsenosides, which have various pharmacological and therapeutic functions.
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