An Efficient and Selective 7‑(Diethylamino)quinolin-2(1)‑One-Chalcone Fluorescent Probe for Detecting Bisulfite in Wine Samples Using a Micellar Solution.

A new probe ()-7-(diethylamino)-3-(3-(4-fluorophenyl)-3-oxoprop-1-en-1-yl)-1-methylquinolin-2-(1)-one () was synthesized and structurally characterized by nuclear magnetic resonance spectroscopy and HRMS. was photophysically characterized by employing UV-vis, fluorescence, and time-resolved fluorescence spectroscopy in combination with computational methods. This probe was studied as a turn-off fluorescent probe based on a Michael addition mechanism for sensing bisulfite (HSO ), which is favored in the presence of an aqueous micellar solution of cetyltrimethylammonium bromide.

Fluorescent Probes Based on 7‑(Diethylamino)quinolin-2(1)‑one Cucurbit[7]uril Complexes for Indicator Displacement Assays: and Experimental Approaches.

In this work, two 7-(diethylamino)-quinolin-2-(1)-one derivatives ( and ) were synthesized and characterized both structurally and physicochemically. The interaction of these derivatives with cucurbit[7]-uril () was explored through combined experimental and approaches, highlighting their unique behavior and practical potential. Experimentally, the complexes exhibited a 1:1 stoichiometry, as confirmed by fluorescence spectroscopy and isothermal titration calorimetry (ITC).

Regioselective Dimerization of Methylcyclopentadiene inside Cucurbit[7]uril.

The molecular confinement within rigid macrocyclic receptors can trigger catalytic activity and steer the selectivity of organic reactions. In this work, the dimerization of methylcyclopentadiene (MCPD) isomers in the presence of cucurbit[7]uril (CB7) was found to display, besides a large rate acceleration, a striking regioselectivity in aqueous solution at pH 3, different from the products predominating in the absence of the supramolecular catalyst. Among the different possible regioisomers and diastereomers, the endo-3,7-dimethyl-3a,4,7,7a-tetrahydro-1H-4,7-methanoindene adduct was selectively formed, which is otherwise found only as a minor product in the dimerization of neat MCPD or in commercial dimeric mixtures.

Polyangiitis with granulomatosis as a paraneoplastic syndrome of B-cell lymphoma of the lacrimal gland.

Introduction. The clinical course of an autoimmune paraneoplastic syndrome parallels the natural history of the primary malignancy. In most cases, such paraneoplastic are syndromes hardly distinguishable from idiopathic autoimmune diseases.