Receiver operating characteristics of computed tomography (CT) compared to cystoscopy in diagnosis of canine ectopic ureters: Thirty-five cases.

Objective: The aim of the study was to determine receiver operating characteristics (ROC) of computed tomographic excretory urography (CTEU) in predicting cystoscopic findings of ureteral anatomy.

Study Design: Retrospective cohort study.

Animals: Thirty-five client-owned dogs.

Radiographic analysis of the dorsal hoof wall thickness in clinically normal draft horses.

Objective: To evaluate the radiographic thickness of the dorsal hoof wall in normal draft horse feet.

Animals: 33 adult draft horses with no history of laminitis, no clinically obvious lameness, and visibly unremarkable front feet were included.

Methods: This was a prospective, descriptive study of clinically normal draft horses' front feet.

MRI and CT characteristics of a grade I meningioma with concurrent cribriform plate lysis in a dog.

A 6-year-old female spayed German Shepherd mixed-breed dog was presented for treatment of a frontal lobe mass diagnosed on MRI, after an acute onset of generalized seizures and behavior changes. Computed tomography of the head was performed for radiation therapy planning and revealed concurrent cribriform plate lysis without nasal sinus invasion, and focal lysis of the left ventrolateral cranial fossa. Histopathology of the mass obtained via surgical excision was consistent with a grade I fibrous meningioma.

Tissue predictability of elastography is low in collagenase induced deep digital flexor tendinopathy.

Elastography is an emerging imaging modality for characterizing tendon injury in horses, but its ability to differentiate tissue deformability relative to treatment group and biochemical properties using a prospective, experimental study design remain unknown. Objectives of the current study were to (a) to investigate differences in glycosaminoglycan, DNA, and soluble collagen levels in mesenchymal stem cell (MSC) treated limbs compared to untreated control limbs utilizing a collagenase model of tendinopathy; (b) compare elastographic features between treatment groups; and (c) determine tissue-level predictive capabilities of elastography in relation to biochemical outcomes. Bone marrow was collected for MSC culture and expansion.

Development of a bio-MEMS device for electrical and mechanical conditioning and characterization of cell sheets for myocardial repair.

Here we propose a bio-MEMS device designed to evaluate contractile force and conduction velocity of cell sheets in response to mechanical and electrical stimulation of the cell source as it grows to form a cellular sheet. Moreover, the design allows for the incorporation of patient-specific data and cell sources. An optimized device would allow cell sheets to be cultured, characterized, and conditioned to be compatible with a specific patient's cardiac environment in vitro, before implantation.

Evaluation of a New Surgical Treatment for Equine Hind Limb Proximal Suspensory Desmitis.

Objective: To evaluate the effects of a new microfracture and ligament splitting procedure on ligament healing and to examine the usefulness of magnetic resonance (MR) imaging for monitoring ligament healing over time using a collagenase model of hind limb proximal suspensory desmitis.

Study Design: Experimental in vivo study.

Animals: Healthy adult horses (n=6).

Comparison of Pneumoperitoneum Volumes in Lift Laparoscopy With Variable Lift Locations and Tensile Forces.

Objective: Evaluate the effect of peritoneal lift location and tensile force on peritoneal volume.

Study Design: Complete randomized block design.

Animals: Eleven fresh canine cadavers.

Advances in equine ultrasonography.

The many advancements in ultrasound technology, including spatial compounding, harmonic imaging, multidimensional and extended field-of-view images, and improvements in transducer capabilities, are used to enhance the ultrasonographic examination of the equine patient. The improvements in software and hardware capabilities help overcome artifacts, improve image quality, and allow better documentation of the examination for follow-up studies. In addition, the ability of smaller, more portable machines to produce better images is ideal for the ambulatory practice setting.

Association between radiographic pattern and outcome in foals with pneumonia caused by Rhodococcus equi.

Our objective was to characterize the association between types of radiographic findings and outcome in foals with pneumonia caused by Rhodococcus equi. Admission lateral thoracic radiographs of 62 foals with culture-confirmed R. equi pneumonia were reviewed retrospectively.

Evaluation of the biliary and brain distribution of technetium Tc 99m sestamibi in healthy dogs with the ABCB1 wildtype genotype before and after treatment with spinosad.

Objective: To determine whether the reported drug-drug interaction between the flea medication spinosad and ivermectin is attributable to inhibition of P-glycoprotein by spinosad.

Animals: 6 healthy adult dogs with the ABCB1 wildtype genotype.

Procedures: The study was conducted as a prospective, masked, randomized crossover design.

Management of hydrops amnion in a mare resulting in birth of a live foal.

Case Description: A 19-year-old Thoroughbred mare was evaluated at 265 days of gestation with a markedly distended abdomen and edema of the ventral portion of the abdomen.

Clinical Findings: The uterus was distended over the pelvic rim, making transrectal palpation of the fetus impossible. Transabdominal ultrasonography revealed excessive amounts of fetal fluid.

Retrospective comparison of azithromycin, clarithromycin, and erythromycin for the treatment of foals with Rhodococcus equi pneumonia.

The objective of this retrospective study was to compare the efficacy of azithromycin-rifampin, clarithromycin-rifampin, and erythromycin-rifampin for the treatment of pneumonia caused by Rhodococcus equi in foals. Eighty-one foals with naturally acquired pneumonia caused by R. equi were included in the study.

Temporal dynamic changes in synthesis of chondroitin sulfate isomers in canine articular chondrocyte culture.

To investigate temporal dynamic changes in the synthesis of chondroitin 6-sulfate (CS6) and chondroitin 4-sulfate (CS4) in vitro, normal articular cartilage of femoral heads was harvested from three dogs. Chondrocytes were isolated and cultured in alginate microspheres for 21 days. On days 7, 14 and 21, DNA content was quantified by fluorometric assay using Hoechst 33258.