Genetic damage and immune dysregulation in Schistosoma haematobium-infected individuals in Nigeria.

Background: Urogenital schistosomiasis caused by affects over 100 million people globally, with potential long-term genetic and immunological consequences poorly understood in endemic populations. This study investigates genetic damage and immune dysregulation in infected individuals from a hyperendemic region in Nigeria.

Objective: To quantify genetic damage markers and characterize immune system alterations in individuals with confirmed infection compared to uninfected controls from Atisbo Local Government Area, Oyo State, Nigeria.