Publications by authors named "Giulia Cuzzani"
Background: Due to the increasing application of the fibroblast activation protein (FAP) targeting radiotracer [Ga]Ga-FAPI-46 in cancer diagnostics by PET/CT, there is a need for a convenient way for routine production of high activities of this tracer. The aim of the current work is the optimization and scale-up of an automated method for [Ga]Ga-FAPI-46 production on a PharmTracer module using two GalliaPharm generators.
Results: Several labeling conditions were evaluated and the best results were obtained with 40 μg of precursor, 3 mg ascorbic acid as anti-radiolysis agent, 0.
Background/objectives: To evaluate T&N-staging diagnostic performance of [68Ga]Ga-FAPI-46 PET/CT (FAPI) in a suspected/confirmed lung cancer surgical cohort.
Methods: Patients were enrolled in a prospective monocentric trial (EudraCT: 2021-006570-23) to perform FAPI, in addition to conventional-staging-flow-chart (including [18F]F-FDG PET/CT-FDG). For the current purpose, only surgical patients were included.
Article Synopsis
- A 73-year-old patient had high levels of Prostate Specific Antigen (PSA) but tests showed no prostate cancer.
- Even though scans and biopsies didn't find cancer, a special PET/CT scan found a suspicious area that turned out to be cancer spread.
- This case shows that the special scan helped doctors figure out what was going on and improved how they treated the patient.