Publications by authors named "Giulia Crudo"
Article Synopsis
- Obstructive sleep apnoea (OSA) is prevalent among elderly patients with cardiovascular issues, yet it often goes unrecognized and untreated.
- The study enrolled 420 patients aged 65+ with paroxysmal atrial fibrillation and moderate to severe OSA to compare the effects of Continuous Positive Airway Pressure (CPAP) treatment against no treatment over an average of 22 months.
- Results showed that CPAP significantly reduced the risk of major cardiovascular events (MACE) and recurrence of atrial fibrillation in patients when combined with regular medical care.
Article Synopsis
- Atrial fibrillation (AF) in older patients is linked to cognitive decline and dementia, with ongoing debate about the benefits of anticoagulants on cognitive function.
- This study involved 983 older patients comparing the cognitive decline between those on non-vitamin K oral anticoagulants (NOACs) and vitamin K antagonists (VKAs) using the Mini Mental State Examination (MMSE) score over an average of 7.2 years.
- Results showed that patients on NOACs had a significantly lesser decline in cognitive function compared to VKAs, indicating that NOACs may be more beneficial for preserving cognitive health in older AF patients despite their higher age and comorbidities.
Obstructive sleep apneas (OSAs) and central sleep apneas (CSAs) are the most common comorbidities in Heart Failure (HF) that are strongly associated with all-cause mortality. Several therapeutic approaches have been used to treat CSA and OSA, but none have been shown to significantly improve HF prognosis. Our study evaluated the effects of a 3-months treatment with sodium-glucose cotransporter type 2 inhibitor (SGLT2i) on polygraphic parameters in patients with sleep apnea (SA) and HF, across the spectrum of ejection fraction, not treated with continuous positive air pressure (CPAP).
View Article and Find Full Text PDF