Role of centers with different patient volumes in the management of rhabdomyosarcoma. An analysis by the Italian Pediatric Soft Tissue Sarcoma Committee.

Procedure: The survival of children with rhabdomyosarcoma (RMS) has gradually improved as a result of the adoption of multidisciplinary treatments. Dedicated skills and facilities are indispensable and more readily available at reference centers. In this study, we examined the role of centers' experience (based on the number of patients treated) in their management of patients with RMS.

Are distinctive risk indicators associated with different stages of caries in children? A cross-sectional study.

Background: Actual caries figures emphasize the need to identify the risk indicators involved in the disease's development. The hypothesis that certain risk indicators might affect the dynamic evolution of the caries process was assessed; to clarify this premise, a cross-sectional survey was performed in school children.

Methods: A total of 390 subjects aged 6-8 years old were randomly selected.

Fluoride content in breast milk after the use of fluoridated food supplement. A randomized clinical trial.

Purpose: To evaluate if the intake of a fluoridated food supplement in breastfeeding mothers increases the fluoride concentration in breast milk.

Methods: A double-blind randomized placebo-controlled study was designed. Two groups of women were formed: a fluoride group (n = 112), using a non-sucrose food supplement containing fluoride (1,500 μg/l for each dose) and a control group (n = 116), using a non-sucrose food supplement without fluoride content.

Early Childhood Caries (ECC) Prevalence and Background Factors: A Review.

Purpose: To describe the prevalence of early childhood caries (ECC) by reviewing published reports and to assess the role of background factors in ECC prevalence.

Materials And Methods: The studies included here consisted of reviews, meta-analyses and randomised clinical trials (RCT) which assessed the prevalence of ECC and included more than 100 subjects and subjects without any stated medical condition. These were in vivo studies published between January 1, 2000 to May 31, 2011.

Early childhood caries and associated determinants: a cross-sectional study on Italian preschool children.

Objectives: This study evaluates the influence of several determinants on the presence of early childhood caries (ECC) in preschool children living in northern Sardinia, Italy. These determinants include the educational level and occupational status of the parents as a proxy for the socioeconomical level (SES) and behavioral factors (dietary and oral hygiene).

Methods: An observational cross-sectional study was designed with a dental examination and a standardized questionnaire.

Natural history of hepatitis C in thalassemia major: a long-term prospective study.

Background: Transfusion-acquired hepatitis C virus (HCV) remains an important problem among patients with thalassemia. In this study, we evaluated the natural history of post-transfusional hepatitis C in thalassemia major, paying special attention to spontaneous viral clearance, to factors influencing the chronicity rate and fibrosis progression.

Design And Methods: A prospective study to evaluate the incidence and etiology of transfusion-related hepatitis was started in 1980.