Nanoemulsions of Cannabidiol, Δ9-Tetrahydrocannabinol, and Their Combination Similarly Exerted Anticonvulsant and Antioxidant Effects in Mice Treated with Pentyelenetetrazole.

The main biologically active molecules of L. are cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC). Both exert anticonvulsant effects when evaluated as single drugs, but their possible interaction as components of extracts has been scarcely studied.

An Alternative Procedure for the Storage and Preservation of Vermamoeba vermiformis and Other Amoebae in the Laboratory.

Free-living amoebae (FLA), particularly Vermamoeba vermiformis and Acanthamoeba spp., have emerged as indispensable models for the study of giant viruses. These organisms provide a unique and efficient system for the isolation and replication of giant viruses, serving as known permissive hosts and thus playing a pivotal role in advancing research in this field.

Effect of Equalized and Nonequalized Resistance Training Volumes on Pain and Disability in Patients With Patellofemoral Pain: A Systematic Review With Meta-Analyses.

To investigate the effect of equalizing and nonequalizing resistance training volume on pain intensity, disability, and strength in individuals with patellofemoral pain (PFP). Intervention systematic review with meta-analysis. MEDLINE, EMBASE, Cochrane, CINAHL, Physiotherapy Evidence Database, Scopus, SPORTDiscus, and Epistemonikos were searched from inception to December 2024.

Pressure-Driven Membrane Processes for Removing Microplastics.

The intense consumption of polymeric materials combined with poor waste management results in the dissemination of their fragments in the environment as micro- and nanoplastics. They are easily dispersed in stormwater, wastewater, and landfill leachate and carried towards rivers, lakes, and oceans, causing their contamination. In aqueous matrices, the use of membrane separation processes has stood out for the efficiency of removing these particulate contaminants, achieving removals of up to 100%.

[Modeling of COVID-19 in Brazil and the interplay between Academia and health managers during the Pandemic].

Modeling played a significant role in underpinning public policy during the COVID-19 pandemic, when decision-making faced a context of limited evidence. This is a cross-sectional study that included and characterized institutions and research groups that worked with COVID-19 modeling and decision-making support. Two strategies were used for identification: 1) scoping review, and 2) group identification by snowball sampling.

Genomic and structural insights into Jyvaskylavirus, the first giant virus isolated from Finland.

Giant viruses of protists are a diverse and likely ubiquitous group of organisms. Here, we describe Jyvaskylavirus, the first giant virus isolated from Finland. This clade B marseillevirus was found in from a composting soil sample in Jyväskylä, Central Finland.

Y-Balance Test after ACL Reconstruction: The relationship with knee and hip muscle strength, ankle dorsiflexion range of motion and postural stability.

Background: Y-Balance Test (YBT) assesses postural stability. When is applied to patients after anterior cruciate ligament reconstruction (ACLR), it is not clear which variables influence its result.

Objective: To connect YBT and postural stability, quadriceps, hamstring, and gluteus complex muscle strength, ankle dorsiflexion range of motion (ADFROM).

Morpho-Physiological Traits and Oil Quality in Drought-Tolerant L. Used for Biofuel Production.

L. is a potential source of raw material for biodiesel fuel due to the high oil content in its grains. In Brazil, this species is cultivated in the low rainfall off-season, which limits the productivity of the crop.

Relevance of the bacteriophage adherence to mucus model for phages.

infections are getting increasingly serious as antimicrobial resistance spreads. Phage therapy may be a solution to the problem, especially if improved by current advances on phage-host studies. As a mucosal pathogen, we hypothesize that and its phages are linked to the bacteriophage adherence to mucus (BAM) model.

Sexual health and access to services for lesbian women in Manaus, Brazil.

This study aims to understand the meanings related to sexual health and the delineations that define the experience of accessing health services for lesbian women in Manaus, Brazil. This study followed a qualitative approach, counting on the participation of ten women who self-reported themselves as lesbians. Semi-structured interviews were carried out and their analyses occurred through three thematic axes.

Immune Response to an Inactivated Vaccine of SARS-CoV-2 (CoronaVac) in an Indigenous Brazilian Population: A Cohort Study.

Introduction: Although the adaptive immune responses to the CoronaVac vaccine are known, their dynamics in indigenous communities remain unclear. In this study, we assessed the humoral and cellular immune responses to CoronaVac (Sinovac Biotech Life Sciences, 2021 NCT05225285, Beijing, China), in immunized Brazilian indigenous individuals.

Methods: We conducted a prospective cohort study on indigenous Brazilian people between February 2021 and June 2021.

Meanings and perceptions of parenthood among transgender men who became pregnant before gender transition.

This qualitative study, with five participating interlocutors, sought to understand the senses and meanings of parenting among trans men who became pregnant before gender transition. Analysis was conducted in light of social theories of gender. The results demonstrated an experience of parenthood subject to a field of tensions and negotiations, as well as subjective production that oscillated between transgression and accommodation of the cultural perspective of their own experience.

Body fat predicts urinary tract infection in kidney transplant recipients: a prospective cohort study.

Background: The association between obesity and infectious diseases is increasingly reported in the literature. There are scarce studies on the association between obesity and urinary tract infection after kidney transplantation (KTx). These studies defined obesity based on body mass index, and their results were conflicting.

The consequences of viral infection on protists.

Protists encompass a vast widely distributed group of organisms, surpassing the diversity observed in metazoans. Their diverse ecological niches and life forms are intriguing characteristics that render them valuable subjects for in-depth cell biology studies. Throughout history, viruses have played a pivotal role in elucidating complex cellular processes, particularly in the context of cellular responses to viral infections.

Seroprevalence Of SARS-COV-2 infection in asymptomatic indigenous from the largest Brazilian periurban area.

This study assessed the seroprevalence of SARS-CoV-2 in 496 asymptomatic individuals from Mato Grosso do Sul, located in Dourados, the largest periurban indigenous area in Brazil, from January 25 to February 4, 2021. The volunteers participated before receiving their first dose of the CoronaVac inactivated vaccine. For screening, blood samples were collected and analyzed using SARS-CoV-2 rapid tests and the enzyme-linked immunosorbent assay (ELISA).

Determining reference ranges for immunological cells of healthy indigenous individuals from a region in Brazil.

Unlabelled: Morais et al. conducted a pioneering study with Brazilian indigenous populations to determine reference values for immunologic cells from healthy adult individuals. The main findings included a higher relative median for T lymphocyte subsets in females than males, and T CD3+, T CD4+, and T CD8+ relative values were statistically different when compared with Brazilian populations from other Brazilian regions.

Lower-Limb Kinematics and Clinical Outcomes: Correlation Does Not Imply Causality.

Letter to the Editor-in-Chief in response to article "Are changes in dynamic knee movement control related to changes in pain or function in people with knee disorders?" by Nunes GS, de Moraes WSLA, de Souza Sampaio V, et al. .

Combining return to sport, psychological readiness, body mass, hamstring strength symmetry, and hamstring/quadriceps ratio increases the risk of a second anterior cruciate ligament injury.

Purpose: To investigate the combinations of variables that comprise the biopsychosocial model domains to identify clinical profiles of risk and protection of second anterior cruciate ligament injury.

Methods: One hundred and forty-five patients for return-to-sport testing after anterior cruciate ligament (ACL) reconstruction (ACLR) were contacted, and 97 were deemed eligible. All were evaluated between 6 and 24 months and followed up for 2 years.

Consumption of cashew nut induced anxiolytic-like behavior in dyslipidemic rats consuming a high fat diet.

This study aimed to evaluate the effect of cashew nut consumption on anxiety-like behavior in dyslipidemic rats. The groups formed were: Control (CONT), Dyslipidemic (DL) and Dyslipidemic cashew nuts (DLCN). Tests to assess anxiety parameters were performed after the treatment period.

Dose-response effect of lower limb resistance training volume on pain and function of women with patellofemoral pain: A systematic review and meta-regression.

Objective: Analyze whether the effects of lower limb resistance training on pain and self-reported function were associated with the exercise volume prescribed for women with patellofemoral pain (PFP).

Methods: A systematic search was undertaken in four databases from inception to May 2023. Eligible trials examined the effects of resistance training programs on pain (visual analogue scale or numerical pain scale) and function (Anterior Knee Pain Scale) in women with PFP.

CALANGO: A phylogeny-aware comparative genomics tool for discovering quantitative genotype-phenotype associations across species.

Living species vary significantly in phenotype and genomic content. Sophisticated statistical methods linking genes with phenotypes within a species have led to breakthroughs in complex genetic diseases and genetic breeding. Despite the abundance of genomic and phenotypic data available for thousands of species, finding genotype-phenotype associations across species is challenging due to the non-independence of species data resulting from common ancestry.

Renal cell carcinoma with contralateral adrenal metastasis: Case report.

Renal cell carcinoma is the major cause of kidney malignancy. Its adrenal metastasis is less frequent and is even rarer when it is affected contralaterally or bilaterally. We present the case of a 55-year-old man with diffuse abdominal pain.