Publications by authors named "Francois Gernier"

Article Synopsis
  • The study focuses on the psychological impact of COVID-19 on older versus younger cancer patients, specifically looking at PTSD symptoms and Quality of Life (QoL).
  • It included 579 patients and used various standardized questionnaires to assess mental health and QoL over a year, with data collected at multiple points during lockdowns and release periods in France.
  • Results showed older patients reported fewer PTSD symptoms and insomnia at the beginning, but cognitive complaints increased over time, eventually matching those of younger patients, with no major differences in the overall mental health trajectory between the two age groups.
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Background: Non-metastatic breast cancer treatment is mainly based on surgery, with or without chemotherapy, radiotherapy and/or hormone therapy. To reduce the risk of hormone receptor positive (HR+) disease recurrence, hormone therapy is prescribed for at least 5 years. It may induce adverse drug reactions (ADRs) as joint pain, sexual dysfunction, weight increase, fatigue, mood disorders and vasomotor symptoms.

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Background: Patients with cancer may be particularly vulnerable to psychological consequences of the COVID-19 pandemic. We studied the prevalence and evolution of posttraumatic stress symptoms (PTSS) in patients with cancer during the pandemic waves, and we investigated factors associated with high symptoms.

Methods: COVIPACT is a 1-year longitudinal prospective study of French patients with solid/hematologic malignancies receiving treatment during the first nationwide lockdown.

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Article Synopsis
  • Germ cell tumors and sex cord stromal tumors are rare ovarian cancers primarily affecting young women, generally treated with conservative surgery and chemotherapy (BEP), which may lead to long-term health issues.
  • The GINECO-VIVROVAIRE study aims to evaluate chronic fatigue, quality of life, and long-term side effects of chemotherapy, especially concerning cardiovascular and pulmonary health in survivors.
  • The study involves comparing 134 ovarian cancer survivors treated with surgery and chemotherapy to control groups, and further medical evaluations will be conducted on a subgroup to assess long-term effects and associated costs.
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Article Synopsis
  • The study investigated the impact of the COVID-19 pandemic on patients with cancer, focusing on the occurrence of PTSD symptoms and changes in their medical care during lockdown.
  • Conducted in France, the research involved 734 patients and found that 21% experienced PTSD, with higher rates among women and those with treatment adjustments.
  • Results showed that PTSD symptoms negatively affected patients’ quality of life, cognition, and increased insomnia, highlighting the need for support during such traumatic events.
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Introduction: Few studies have explored the long-term occupational situation after cancer. The aim of our study were to study the employment status among long-term cancer survivors and to compare it to cancer-free controls from the general population at 5, 10 or 15 years after cancer diagnosis.

Methods: From data of a registry-based study, long-term survivors from breast,cervical and colorectal cancer, randomly selected from three tumor registries in France, were compared to cancer-free controls randomly selected from electoral lists.

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Background: While several studies have documented fatigue during and after cancer treatment, long-term cancer survivor fatigue is underreported. In this study, we compare fatigue, quality of life (QoL), and anxiety between relapse-free cancer survivors 15 years after diagnosis and healthy controls.

Methods: Cancer survivors (CS) were randomly selected from three large population-based cancer registries (Bas-Rhin, Calvados, and Doubs, France).

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