Kilometric sea level changes during the Messinian salinity crisis caused by river erosion and climate.

The Messinian salinity crisis (MSC) was a short period of isolation of the Mediterranean Sea that caused the precipitation of a million cubic kilometers of salt. The puzzling sedimentary record that formed after this deposition yields conflicting values of the extent of desiccation. Estimations range from a full exposure of most of the Mediterranean seafloor based on shallow fossil fauna found in the abyss to a nearly full Mediterranean scenario as suggested by similar, fresher-water deposits ubiquitous along the coastline: the so-called Lago-Mare formation.

Ultra High-Density Mapping and Ablation of Localized Micro-Reentrant Tachycardias: Insight From the CHARISMA Registry.

Background: Recent advancements in ultra-high-density mapping (UHDM) featuring automated functionalities have enhanced our understanding of micro-reentrant atrial tachycardias (mAT) circuits and the precise localization of the origin.

Purpose: To evaluate the diagnostic support provided by an automated UHDM algorithm in guiding the ablation of mATs.

Methods: Consecutive patients eligible for AT ablation in 22 Italian centers were prospectively enrolled.

Effect of rate-adaptive atrial support compared to VDD pacing in cardiac resynchronization therapy recipients: A randomized cross-over study.

Background: Cardiac resynchronization therapy (CRT) is a cornerstone treatment for heart failure, yet the optimal pacing mode remains uncertain. This study investigates the impact of DDDR (rate-adaptive atrial support) versus VDD pacing modes on functional capacity and echocardiographic outcomes in patients with CRT-defibrillators.

Methods: In a multicenter, double-blind, crossover trial, 26 sinus rhythm patients undergoing CRT-defibrillator implantation were randomized to DDDR at 60 beats-per-minute or VDD at 30 beats-per-minute.

Late Miocene transformation of Mediterranean Sea biodiversity.

Understanding deep-time marine biodiversity change under the combined effects of climate and connectivity changes is fundamental for predicting the impacts of modern climate change in semi-enclosed seas. We quantify the Late Miocene-Early Pliocene [11.63 to 3.

The marine biodiversity impact of the Late Miocene Mediterranean salinity crisis.

Massive salt accumulations, or salt giants, have formed in highly restricted marine basins throughout geological history, but their impact on biodiversity has been only patchily studied. The salt giant in the Mediterranean Sea formed as a result of the restriction of its gateway to the Atlantic during the Messinian Salinity Crisis (MSC) 5.97 to 5.