Dynamism, Sensitivity, and Consequences of Mesenchymal and Stem-Like Phenotype of Cancer Cells.

There are remarkable similarities in the description of cancer stem cells (CSCs) and cancer cells with mesenchymal phenotype. Both cell types are highly tumorigenic, resistant against common anticancer treatment, and thought to cause metastatic growth. Moreover, cancer cells are able to switch between CSC and non-CSC phenotypes and vice versa, to ensure the necessary balance within the tumor.

Integrated assessment of air pollution using observations and modelling in Santa Cruz de Tenerife (Canary Islands).

The present study aims to analyse the atmospheric dynamics of the Santa Cruz de Tenerife region (Tenerife, Canary Islands). This area is defined by the presence of anthropogenic emissions (from a refinery, a port and road traffic) and by very specific meteorological and orographic conditions-it is a coastal area with a complex topography in which there is an interaction of regional atmospheric dynamics and a low thermal inversion layer. These factors lead to specific atmospheric pollution episodes, particularly in relation to SO2 and PM10.

[Impact of a clinical self-evaluation intervention on the appropriateness of hospital stays].

Aim: To assess the impact of an intervention on inappropriate hospital stays (IHS) in acute-care hospitals in Catalonia (Spain) with the aim of testing the hypothesis that a simple intervention (adeQhos) reduces the proportion of IHS.

Methods: A pre-test/post-test study was performed through the <> questionnaire. Two intervention groups (internal medicine and general surgery) and 2 control groups (other medical specialities, orthopedics) were compared in 10 acute-care hospitals in Catalonia.

[Quick and early diagnostic outpatient unit: an effective and efficient assistential model. Five years experience].

Background And Objective: To analyze the applicability of an out-patient Quick and Early Diagnostic Unit (QEDU) to evaluate patients with a potential life-threatening disorder on an out-patient basis.

Patients And Method: We analyzed prospectively all patients attended in the unit for five years (1997-2001). We compared patients with lung cancer and colorectal cancer admitted to hospital for conventional study versus patients studied at the unit.