Publications by authors named "Florine L Boer"
Article Synopsis
- Mucosal melanoma (MM) is a rare and aggressive cancer, with the study examining its incidence and survival trends in the Netherlands from 1990-2019, amidst advancements in treatment options for melanoma.
- The research found that 1496 cases were diagnosed, predominantly in women and often at an advanced stage, with a consistent incidence rate and a 5-year overall survival (OS) rate of only 24%.
- While immune and targeted therapies have improved outcomes for MM patients, they still face a worse prognosis compared to those with cutaneous melanoma (CM), highlighting the need for further research to enhance treatment effectiveness.
Objective: To identify clinicopathological characteristics, treatment patterns, clinical outcomes and prognostic factors in patients with vulvar melanoma (VM).
Materials & Methods: This retrospective multicentre cohort study included 198 women with VM treated in eight cancer centres in the Netherlands and UK between 1990 and 2017. Clinicopathological features, treatment, recurrence, and survival data were collected.
Survival outcomes of patients with advanced mucosal melanoma diagnosed from 2013 to 2017 in the Netherlands - A nationwide population-based study.
Eur J Cancer
September 2020
Background: Mucosal melanoma (MM) is rare and has a poor prognosis. Since 2011, new effective treatments are available for advanced melanoma. It is unclear whether patients with mucosal melanoma equally benefit from these new treatments compared with patients with cutaneous melanoma (CM).
View Article and Find Full Text PDFVulvar malignant melanoma (VMM) is a rare disease, accounting for 5% of all vulvar malignancies and is characterized by low survival and high recurrence rates. It is considered as a distinct entity of mucosal melanoma. Prognostic factors are higher age, advanced Breslow thickness, and lymph node involvement whilst central localization and ulceration status are still under debate.
View Article and Find Full Text PDFPurpose: Autotransplantation of ovarian tissue can be used to restore fertility in patients with cancer following gonadotoxic treatment. Whether this procedure is safe remains unclear, as current tumor detection methods render the ovarian tissue unsuitable for transplantation. Full-field optical coherence tomography (FF-OCT) is an imaging modality that rapidly produces high-resolution histology-like images without the need to fix, freeze, or stain the tissue.
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