Real-life preliminary evidence for basophils as predictors of Tezepelumab response in severe asthma.

Background: Severe asthma is a complex disease with persistent symptoms despite high-dose inhaled therapy. Tezepelumab, a monoclonal antibody targeting thymic stromal lymphopoietin (TSLP), has shown efficacy across asthma phenotypes. However, identifying early responders remains a challenge.

Diaphragm function in patients with asthma and healthy controls: A cross-sectional study.

Background: Asthma is a chronic respiratory disease characterized by airway inflammation and variable respiratory symptoms. While peripheral muscle deconditioning is known to affect lung function and exercise tolerance, the role of respiratory muscle dysfunction, particularly the diaphragm, remains underexplored.

Objective: We aim to evaluate potential differences in diaphragm function in patients with asthma.