The Association between β-Thalassemia Major (β-TM) and Cardiac Complications: Recent Insights.

β-thalassemia Major (β-TM) is a severe hereditary disorder characterized by insufficient synthesis of β-globin chains, resulting in chronic anemia and lifelong dependence on regular blood transfusions. Despite advancements in therapeutic modalities, cardiac complications, including atrial fibrillation, cardiomyopathy, and pulmonary hypertension, continue to be significant contributors to morbidity and mortality among β-TM patients. These persistent cardiovascular risks underscore the urgent need for early, accurate detection and the implementation of personalized assessment strategies to improve patient outcomes.