Publications by authors named "Filippo Paoletti"

Background/objectives: The principles of value-based healthcare (VBHC) have received widespread endorsement, leading healthcare organizations worldwide to shift their strategies towards them. However, despite growing recognition and acceptance, the actual implementation of value-based approaches varies widely. This research aims to identify studies that address the implementation of VBHC at different levels (healthcare policymakers, hospital administrators, and healthcare providers), focusing on each level's relative strategies.

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  • Multigene panels analyze genes related to breast cancer risk, helping to identify at-risk individuals in affected families.
  • A multidisciplinary team is essential for managing breast cancer due to the complexity of genetic variants and their clinical implications.
  • Genetic testing and counseling are crucial for personalized treatment and prevention strategies, reflecting the dynamic nature of guidelines and research in breast cancer management.
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  • Global chronic kidney disease is on the rise, prompting a need for more living donors, including those with obesity, despite some health risks associated with obesity in donors.
  • Bariatric surgery can help mitigate these risks, with studies indicating that procedures like sleeve gastrectomy are effective and can make obese candidates suitable for kidney donation after appropriate weight loss.
  • The research emphasizes that while bariatric surgery can benefit obese donors, it should be seen as a way to improve individual health rather than simply expanding the donor pool.
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Background: Rising incidence and prevalence of end-stage renal disease is a worldwide concern for sustainability of healthcare systems and societies. Living donor renal transplant [LDRT] provides highest health achievements and cost containment than any alternative form of renal replacement therapy. Nonetheless, about 25% of potential LDRTs are missed for causes directly related with inadequate timing in donor assessment.

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Introduction: Cancer is the second most common cause of mortality and morbidity in Kidney Transplant Recipients (KTRs). Immunosuppression can influence the efficacy of cancer treatment and modification of the immunosuppressive regimen may restore anti-neoplastic immune responses improving oncologic prognosis. However, patients and transplant physicians are usually reluctant to modify immunosuppression, fearing rejection and potential graft loss.

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Obesity is associated with chronic metabolic conditions that directly and indirectly cause kidney parenchymal damage. A review of the literature was conducted to explore existing evidence of the relationship between obesity and chronic kidney disease as well as the role of bariatric surgery in improving access to kidney transplantation for patients with a high body mass index. The review showed no definitive evidence to support the use of a transplant eligibility cut-off parameter based solely on the body mass index.

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The purpose of this study was to evaluate and quantify the effects of Ultra-Low Frequency Transcutaneous Electrical Nerve Stimulation (ULF-TENS) on the Central Nervous System, using electroencephalography. The research was conducted on a study group of twelve patients, and a control group of six. Patients were chosen between the ages of twenty and thirty years old, and all had occlusal flags without pain.

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