Vascular imbalance in polycystic ovary syndrome: Insights into endothelial dysfunction.

Polycystic ovary syndrome (PCOS) is a multifactorial endocrine disorder associated with vascular dysfunction and increased cardiovascular risk. This study aims to investigate the dysregulation of vascular tone in PCOS, focusing on the imbalance between vasodilators (nitric oxide [NO] and apelin) and vasoconstrictors (noradrenaline and reduced prostacyclin). By examining these factors, the study seeks to elucidate their contribution to endothelial dysfunction and cardiovascular complications in PCOS patients.

Effects of the february 6 earthquake on the agents growing in urine cultures and antibiotic resistance rates.

Objective: The aim of this study was to investigate the effects of the February 6 earthquake on the bacteria grown in urine cultures and antibiotic resistance of patients admitted to the urology outpatient clinic.

Methods: In this study, 11,397 urine samples requested by the urology outpatient clinic between January 2022 and December 2023 were examined. We evaluated the urine cultures and antibiotic resistance profiles of the pathogens in patients' clinic in the years 2022 and 2023 separately and post-earthquake year 2023 as two separate periods, as the first 6-month period immediately after the earthquake.

Oxygen regulated protein 150 can be considered as a severity indicator in obstructive sleep apnea.

Oxygen-regulated protein 150 (ORP150) is a chaperone found in the endoplasmic reticulum (ER) induced by ER stress, oxidative stress, glutamate toxicity, ischemia, and hypoxia. Increased expression of ORP150 protects the cells by stopping ER stress, maintaining calcium balance, and delaying apoptosis. In this study, we aim to investigate serum ORP150 amount in patients with different severity levels of obstructive sleep apnea (OSA).

Determining the relationship between e-health literacy and personal health system and patient satisfaction using structural equation model: an example of a training and research hospital.

Background: In the current technology landscape, several individuals electronically stores their health information. The personal health system offers significant conveniences to users, hence enhancing patient satisfaction. Assessing the impact of e-health literacy, personal health system, and patient happiness on enhancing patient satisfaction an essential outcome of health services is crucial for system improvement and clarity.

Evaluation of Disability and Physical Performance Based on Mechanical and Inflammatory Component in Chronic Low Back Pain.

Objective: The aim of this study was to perform the validity and reliability analysis of the Turkish-language version of the Mechanical and Inflammatory Low Back Pain Index (MILBPI), which is used to determine mechanical and inflammatory components in chronic low back pain (CLBP). The effects of mechanical and inflammatory components on disability and physical performance in patients with CLBP were investigated.

Material And Method: In the first phase of the study, 120 CLBP patients aged 18-65 years were included in the Turkish-language version validity and reliability analysis of MILBPI.

Significant correlation between serum DOTL1 levels and pain intensity, sensitivity, and psychological distress in women with fibromyalgia.

Disruptor of telomeric silencing 1-like (DOT1L) is a protein involved in epigenetic regulation, as well as in the Wnt and hypoxia signaling pathways. DOT1L has been found to play a role in the pathogenesis of various diseases associated with these pathways. In this study, it was aimed to determine serum DOT1L levels in patients with fibromyalgia (FM) and its association with disease activity.

Correlation of Neuroanatomical Structures Related to Speech in Cerebral Palsy Patients Aged 0-17: A Retrospective MRI Study.

: Cerebral Palsy (CP) is a non-progressive clinical condition characterized by secondary issues, including speech impairments. Our study aims to evaluate the volumes of brain areas related to speech in patients diagnosed with CP between the ages of 0-17. : this study includes the images of 84 children: 42 in the control group who applied to the hospital between the specified dates and were reported as healthy by MRI from the patient records, and 42 patients with CP.

Corrigendum to "Association of 2D:4D finger length ratio of People Working in different professions with personality traits" [Heliyon 10(11) June 2024 e32332].

[This corrects the article DOI: 10.1016/j.heliyon.

The Relationship of the Psychological Resilience and Stress Coping Level of Health Personnel Working in Hospitals After Kahramanmaraş-Based Earthquakes with Traumatic Stress.

Objectives: In this study, we aimed to examine the indirect and direct effects of the stress experienced by health workers after an earthquake on their psychological resilience.

Methods: This study was conducted using the Structural Equation Model on 315 employees serving in hospitals in Kahramanmaraş, Gaziantep, Şanlıurfa, Diyarbakır, Adana, Adıyaman, Osmaniye, Hatay, Kilis, Malatya, and Elazığ (11 provinces) that were most affected by the earthquake.

Results: The study group consisted of 58.

Is the Family Health Center Professionals' Knowledge Level About Child Abuse and Neglect Sufficent? A Comprehensive Field Study.

Background: Child abuse and neglect bring lots of undesirable consequences for the future of children and societies with it. It is expected that health service providers have sufficient knowledge about that subject in order to determine abuse and neglect.

Materials And Methods: In this study, a 67-item scale with a Cronbach's alpha value of 0.

Investigation of the Effects of Light, Darkness, and Dim Light on Rat Brain Tissue: A Biochemical and Histological Study.

This study evaluates acetylcholinesterase (AChE) enzyme activity levels, oxidative stress parameters, histopathological findings, and serum melatonin levels in rat brain tissue. 32 male Wistar Albino rats were randomly divided into four groups: Control, Light, Dark, Dim light ( = 8 each group). After a 30 day experiment, brain tissues were collected to measure AChE, glutathione S-transferase (GST), glutathione (GSH), and malondialdehyde (MDA) levels and conduct histopathological analyses.

Evaluation of volume measurements of neuroanatomical structures related to speech in multiple sclerosis patients.

Background/aim: Individuals with multiple sclerosis (MS) may experience various speech-related issues, including decreased speech rate, increased pauses, and changes in speech rhythms. The purpose of this study was to compare the volumes of speech-related neuroanatomical structures in MS patients with those in a control group.

Materials And Methods: The research was conducted in the Neurology and Radiology Departments of Malatya Training and Research Hospital.

Association of 2D:4D finger length ratio of People Working in different professions with personality traits.

Background: The ratio of the index finger (2nd finger) to the ring finger (4th finger) (2D:4D) can give information about harmony between personality and career of individuals. The developing technology makes it difficult to choose a profession.

Aim: This study aims to contribute to the career choice of individuals by analyzing the relationship between the 2D:4D finger digit ratio and personality traits of individuals working in different professions (Educator, Worker, Housewife, Civil servant, Healthcare professional/EWHCH).

Classification of Osteophytes Occurring in the Lumbar Intervertebral Foramen.

Background: Surgeons have limited knowledge of the lumbar intervertebral foramina. This study aimed to classify osteophytes in the lumbar intervertebral foramen and to determine their pathoanatomical characteristics, discuss their potential biomechanical effects, and contribute to developing surgical methods.

Methods: We conducted a retrospective, non-randomized, single-center study involving 1224 patients.

Relationship between parental adverse childhood experiences and the prevalence of early childhood caries.

Objectives: The aim of this study was to examine the behavioural health conditions associated with parents' retrospective adverse childhood experiences (ACEs) scores and their children's early childhood caries (ECC) in parent-child dyads.

Materials And Methods: Parents with children younger than 72 months were included in the study. A relational screening model was used.

The Effects of Workload Excess on Quality of Work Life in Third-Level Healthcare Workers: A Structural Equation Modeling Perspective.

Examining the workload and working conditions of healthcare workers is crucial regarding the quality of the work life of employees and the quality of services provided. This study aims to determine the effects of the perceptions of workload on the quality of work life of health personnel working in two different tertiary hospitals affiliated with the Ministry of Health and the Higher Education Institution in Türkiye with structural equation modeling. This study was conducted in two hospitals in Malatya province: İnönü University Turgut Özal Medical Center affiliated with the Higher Education Institution and Malatya Training and Research Hospital affiliated with the Ministry of Health.

Effects of the Kahramanmaras, Turkey 2023 earthquakes on balance perception, dizziness and post-traumatic stress: A relational screening model between subjective balance problems and post-traumatic stress.

Objective: The aim of the present study was to investigate the effects of the February 6, 2023, earthquakes in Turkey and recurrent aftershocks on balance and post-traumatic stress in surviving victims.

Methods: Our study included 1004 participants aged 18-65 years who were exposed to the February 6 earthquakes and aftershocks in Turkey. After obtaining online consent from all participants, the Vertigo Symptom Scale (VSS), the Dizziness Handicap Index (DHI), and the Posttraumatic Post-Traumatic Disorder Checklist Scale (PCL-5) were administered online, and the interactions between the variable sets were examined using a correlational screening model.

Ameliorative Effects of Larazotide Acetate on Intestinal Permeability and Bacterial Translocation in Acute Pancreatitis Model in Rats.

Background: Intestinal barrier dysfunction in acute pancreatitis (AP) may progress to systemic inflammatory response syndrome (SIRS) and multi-organ failures by causing bacterial translocation. Larazotide acetate (LA) is a molecule that acts as a tight junction (TJ) regulator by blocking zonulin (Zo) receptors in the intestine.

Aims: In our study, we aimed to investigate the effects of LA on intestinal barrier dysfunction and bacterial translocation in the AP model in rats.

Evaluation of Turkish Academic and Student Attitudes on Plagiarism: Validity and Reliability of the Plagiarism Attitudes Scale.

The main purpose of this study was to translate the Plagiarism Attitude Scale into Turkish and validate it for use in Turkish settings, in order to better understand research integrity attitudes and awareness of the Turkish academic and student community, while also contributing an instrument for research in this area. The research was designed and conducted with 483 participants. In the process of adapting the scale to Turkish, language, content, and construct validity analyses were performed.

Determining medical students' anxiety and readiness levels about artificial intelligence.

The aim of this study is to determine the levels of anxiety and readiness among medical students regarding artificial intelligence (AI) and examine the relationship between these factors. The research was conducted on medical students, and the data was collected through face-to-face and online surveys between April and June 2022. The study utilized a socio-demographic information form, an AI anxiety scale, and a medical AI readiness scale.

Evaluation of possible associated factors for early childhood caries: are preterm birth and birth weight related?

Background: This study aimed to evaluate the oral and dental health of preschool children aged 12-71 months living in the Eastern Anatolia Region of Turkey, and to examine the effects of low birth weight (LBW) and preterm, early term and term birth on dental caries.

Methods: 475 participants were included in the study. Intraoral examinations were performed and evaluated for the presence of early childhood caries (ECC).

Assessing lipoxin-mediated inflammatory responses in the second trimester of pregnancy among women with obesity: A comprehensive analysis.

Objective: This study aimed to explore the relationship between maternal plasma lipoxin A4 (LXA4) levels during the second trimester of pregnancy and certain proinflammatory molecules, such as interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α), as well as the antiangiogenic factor vascular endothelial growth factor receptor 1 (VEGFR-1), in conjunction with obesity among pregnant women.

Materials And Methods: A total of 30 pregnant women with obesity were compared with 30 pregnant women of normal weight, matched for both age and gestational week. Plasma samples were collected from all participants between the 18 and 28 weeks of pregnancy.

Cancer Metastasis Prediction and Genomic Biomarker Identification through Machine Learning and eXplainable Artificial Intelligence in Breast Cancer Research.

Aim: Method: This research presents a model combining machine learning (ML) techniques and eXplainable artificial intelligence (XAI) to predict breast cancer (BC) metastasis and reveal important genomic biomarkers in metastasis patients.

Method: A total of 98 primary BC samples was analyzed, comprising 34 samples from patients who developed distant metastases within a 5-year follow-up period and 44 samples from patients who remained disease-free for at least 5 years after diagnosis. Genomic data were then subjected to biostatistical analysis, followed by the application of the elastic net feature selection method.

Is there a relationship between Haller Index and cardiopulmonary function in children with pectus excavatum?

Background: This study aims to systematically examine the cardiopulmonary functions in children with pectus excavatum and to compare the obtained findings with the Haller Index.

Methods: Between September 2017 and June 2018, medical records of a total of 31 patients (27 males, 4 females; mean age: 14.8±2.