Publications by authors named "Fengyin Huang"
Characterization of the Hemolytic Activity of Mastoparan Family Peptides from Wasp Venoms.
Toxins (Basel)
September 2023
Article Synopsis
- Biologically active peptides, particularly mastoparans from wasp venom, show potential for drug development due to their various biological effects, but their hemolytic activity poses challenges for clinical use.
- A study of 55 mastoparans revealed differing levels of hemolytic activity, with 18 exhibiting strong, 14 moderate, and 23 minimal hemolytic effects, highlighting molecular diversity among these peptides.
- Further analysis indicated that hydrophobicity is key to hemolytic activity, and four specific mastoparans (Parapolybia-MP, Mastoparan-like peptide 12b, Dominulin A, and Dominulin B) were identified as promising
Promotion of HepG2 cell apoptosis by Sedum emarginatum Migo and the mechanism of action.
BMC Complement Med Ther
January 2022
Background: Sedum emarginatum Migo(S. emarginatum) has anti-tumor and anti-oxidant effects. This study aimed to screen the extractions of S.
View Article and Find Full Text PDFFingerprint and multi-index content determination of ethyl acetate extract of Sedum emarginatum Migo.
Pak J Pharm Sci
September 2021
Sedum emarginatum Migo (Aoyejingtian) is a perennial succulent herb of the sedum genus in the family Crassulaceae, which has the fountion of treating furuncle, swelling and haematemesis, hematochezia, menorrhagia and hepatitis. Preliminary studies of our research group had showed that the ethyl acetate extract of Sedum emarginatum Migo could inhibit the proliferation of liver cancer HepG2 cells. The establishment of a reasonable and feasible quality evaluation method for the effective parts of Sedum emarginatum Migo can provide a scientific basis for the further development and utilization of Sedum emarginatum Migo.
View Article and Find Full Text PDFSanpao herbs inhibit development of atopic dermatitis in Balb/c mice.
Asian Pac J Allergy Immunol
June 2014
Objective: To explore the effects of SANPAOCAO (SPC), a compound traditional Chinese folk medicine, on chronic dermatitis/eczema in mice induced by 2, 4-dinitrochlorobenzene (DNCB).
Methods: Thirty-three Balb/c mice were randomly divided into a negative control group, a positive control group, a prednisolone treatment group, an SPC ethanol extract treatment group, a Cardiospermum halicacabum ethanol extract treatment group, a Physalis minima ethanol extract treatment group, and a Jussiaea repens ethanol extract treatment group. Mice in the six treatment groups had twenty-five microliters of 0.