Targeted Phenolic Profiling, Antioxidant Activities, and Enzyme Inhibition Potential of Campanula lyrata subsp. lyrata Extracts With Molecular Docking Insights.

The growing interest in plant-based bioactives has intensified research into their therapeutic potential. This study investigated the chemical profile, antioxidant properties, and enzyme inhibitory effects of methanol extracts from Campanula lyrata subsp. lyrata, obtained via maceration (MAC-ME), Soxhlet (SOE-ME), and ultrasound-assisted extraction (UAE-ME).

The importance of CYP1B1 polymorphism in obesity.

Obesity is a multifactorial disease, commonly observed both worldwide and in our country, triggered by environmental and genetic factors, adversely affecting all physiological functions of the body, and leading to an increase in body fat mass. Although various variants associated with susceptibility to obesity have been identified in genomic studies, these variants explain only a small portion of the genetic basis of obesity. This case-control study investigates, for the first time in the Turkish population, the relationship between CYP1B1 gene rs1056827 and rs1056836 polymorphisms in obesity patients undergoing surgical intervention (bariatric surgery).

Ultrasound-assisted extraction of : phytochemical profile, antioxidant potentials via RACI analysis, and enzyme inhibitory activities.

Understanding the bioactive potential of plant extracts requires detailed evaluations of their chemical composition and bioactivities. This study investigated the chemical profiles, antioxidant properties, and enzyme inhibitory activities of water and methanol extracts of Ayasligil & P.H.