Screening donated blood for transfusion-transmitted infections (TTIs) is a critical component of transfusion safety, particularly in high-demand regions such as Makkah City, Saudi Arabia. This study is aimed at assessing the seroprevalence of TTI markers among blood donors at King Abdulaziz Hospital-Makkah (KAHM) over a 7-year period. In this retrospective study, 17,661 individuals who donated blood at the KAHM, Saudi Arabia, from January 2017 to December 2023, were included.
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