Publications by authors named "Fanny Delehaye"
Background: Ovarian mature teratomas (OMTs) are the most common benign ovarian tumors in pediatric patients. Management in adolescents can be performed by pediatric (PSs) or gynecologic surgeons (GSs). The aim of this study was to assess the differences in OMT management and the repercussions according to the risk of secondary events.
View Article and Find Full Text PDFBronchial Carcinoid Tumors in Children and Adolescents.
Pediatr Blood Cancer
August 2025
Purpose: Carcinoid neoplasms, even rare, are the most common pulmonary tumors during childhood. They are classically divided into typical and atypical tumors according to pathology pattern. Cornerstone therapy is to obtain a complete tumor resection.
View Article and Find Full Text PDFFamilial History in Ovarian Teratomas Is a Frequent Event: 22 Years' Experience at a Single Center.
Pediatr Blood Cancer
April 2025
Background: Ovarian mature teratoma represents the most common benign neoplasm among pediatric germ cell tumors. This study reports the prevalence and characteristics of familial forms identified in a single center over 22 years in order to better understand possible familial predispositions to ovarian teratoma.
Methods: The records of all patients who were surgically treated for ovarian teratoma between 2000 and 2022 were retrospectively reviewed.
Background And Aims: Primary lung tumors (PLTs) in children are rare, and surgery remains the key to ensure remission. Here we describe the PLTs clinical characteristics, their management, and the pulmonary outcome following surgery.
Methods: We carried out a French national cohort of pediatric PLTs from 2013 to 2023 from the FRACTURE rare pediatric tumors national database.
Impact of socioeconomic factors on time to diagnosis of childhood cancer.
Pediatr Hematol Oncol
February 2025
Article Synopsis
- The study investigates the relationship between socioeconomic status (SES) and time to diagnosis (TTD) in childhood cancer, noting that a clearer connection has been observed in adults.
- A retrospective analysis involving 854 children revealed a median TTD of 28 days, with variations based on tumor type but no significant link between SES factors and TTD.
- Initial treatment by non-specialized professionals was associated with longer TTD, while overall, TTD did not appear to influence children's survival or relapse rates, indicating a need for further research on individual SES impacts.
Article Synopsis
- Chest pain is common in pediatric emergencies, with most causes being benign; however, chest x-rays (CXR) are frequently ordered despite low rates of abnormalities.
- A study reviewed medical records of 599 children to assess the adherence of physicians to guidelines for CXR usage, finding that 57.1% followed the recommended algorithm and only 8.2% had abnormal CXR results.
- The findings suggest the need for improved guidelines for CXR prescriptions based on specific clinical indicators of chest pain, as current practices may overuse this test despite its limited diagnostic value.
Background: Treatment summaries and a personalized survivorship care plans based on internationally approved, organ-specific follow-up care recommendations are essential in preserving the health and quality of life for cancer survivors. Cohorts made up of survivors of childhood cancer have made significant contributions to the understanding of early mortality, somatic late complications, and psychosocial outcomes among former patients. New treatment protocols are needed to enhance survival and reduce the potential risk and severity of late effects, and working with treatment databases is crucial in doing so.
View Article and Find Full Text PDFArticle Synopsis
- The study analyzed the prevalence and impact of anemia in children diagnosed with chronic myeloid leukemia (CML), highlighting that 81% of 430 patients had anemia at diagnosis, with many experiencing moderate to severe cases.
- Moderate and severe anemia were linked to younger age, symptoms like fatigue, and higher blood cell counts, leading to delays in effective treatment response with imatinib.
- Although anemia was common and influenced treatment outcomes, it did not significantly affect overall survival rates in pediatric CML patients.
Unusual recurrence of sacrococcygeal mature teratoma: A case report.
Pediatr Blood Cancer
April 2023
Background: Ovarian mature teratoma (OMT) is a common ovarian tumor found in the pediatric population. In 10%-20% of cases, OMT occurs as multiple synchronous or metachronous lesions on ipsi- or contralateral ovaries. Ovarian-sparing surgery (OSS) is recommended to preserve fertility, but total oophorectomy (TO) is still performed.
View Article and Find Full Text PDFHematopoietic Stem Cell Transplantation for Hepatitis-associated Aplastic Anemia Following Liver Transplantation for Nonviral Hepatitis: A Retrospective Analysis and a Review of the Literature by the Severe Aplastic Anemia Working Party of the European Society for Blood and Marrow Transplantation.
J Pediatr Hematol Oncol
October 2021
Hepatitis-associated aplastic anemia (HAAA) has been reported in 23% to 33% of patients who received orthotopic liver transplantation (LT) for acute liver disease of unknown origin (nonviral hepatitis). In this situation, hematopoietic stem cell transplantation (HSCT) might be a curative option. Here the authors report on 6 patients who received HSCT after LT for nonviral HAAA hepatitis.
View Article and Find Full Text PDFBackground: Hepatitis-associated aplastic anemia (AA) is a rare syndrome combining acute hepatitis of variable severity and AA. Hepatitis may be severe enough to require urgent liver transplantation (LT). Herein, we describe clinical presentation and management of a cohort of pediatric patients diagnosed with AA after undergoing LT for nonviral hepatitis.
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