Immunogenicity and Protective Capacity of a Virus-like Particle Vaccine against Type 3 Secretion System Tip Protein, CT584.

An effective vaccine against is urgently needed as infection rates continue to rise and causes reproductive morbidity. An obligate intracellular pathogen, employs a type 3 secretion system (T3SS) for host cell entry. The tip of the injectosome is composed of the protein CT584, which represents a potential target for neutralization with vaccine-induced antibody.