Effect of 20-μm-Thin Ceramic Coatings of Hydroxyapatite, Bioglass, GB14 and β-TCP With Copper on the Ingrowth Behavior of Femoral Implants.

Aseptic loosening and infection are still the main reasons for revision surgery. The contact of the implant is made through the surface, which is coated with calcium phosphate ceramics for better integration into the bone. The aim of the present work is to optimize these coatings by making them thinner (20 μm) and doping them with copper to add antimicrobial functionality.

Effect of 20 μm thin ceramic coatings of hydroxyapatite, bioglass, GB14 and Beta-Tricalciumphosphate with copper on the biomechanical stability of femoral implants.

In the present work, we test four thin coatings for titanium implants, namely, bioglass, GB14, Beta-Tricalciumphosphate (β-TCP) and hydroxyapatite (HA) with and without incorporated copper ions for their osteointegrative capacity. A rabbit drill hole model for time intervals up to 24 weeks was used in this study. Implant fixation was evaluated by measuring shear strength of the implant/bone interface.