The role of pharmacomicrobiomics in HIV prevention, treatment, and women's health.

In the absence of an effective vaccine or curative treatment for HIV, the global HIV/AIDS epidemic continues despite significant advances in treatment and prevention. Antiretroviral therapy (ART) drugs have transformed HIV from a terminal illness to a manageable chronic condition. Likewise, pre-exposure prophylaxis treatment (PrEP) has dramatically reduced transmission in some of the highest risk populations.

Decrypting phytomicrobiome of the neurotoxic actinorhizal species, , and dispersal boundary of cluster 2 in soil outward compatible host rhizosphere.

The actinorhizal plant, is a neurotoxic plant species endemic to the western Mediterranean area, which forms a nitrogen-fixing symbiosis with members of cluster 2. Contrarily to other clusters, the occurrence and mode of dispersal for infective cluster 2 units outside of the host plant rhizosphere remains controversial. The present study was designed to investigate the structure of the microbiomes of phytosphere, rhizosphere, and soil samples extending outward linearly up to 1 km.

Draft Genome Sequences for the sp. strains CgS1, CcI156 and CgMI4, Nitrogen-Fixing Bacteria Isolated from sp. in Egypt.

sp. strains CgS1, CcI156 and CgMI4 were isolated from and C. nodules.

Draft Genome Sequence for sp. Strain BMG5.11, a Nitrogen-Fixing Bacterium Isolated from Elaeagnus angustifolia.

sp. strain BMG5.11, which was isolated from nodules, is able to infect other actinorhizal plants, including , , , , and Here, we report the 11.

Draft Genome Sequence of the Symbiotic sp. strain B2 isolated from root nodules of found in Algeria.

sp. strain B2 was isolated from nodules Here, we report the 5.3-Mbp draft genome sequence of sp.

Draft Genome Sequences of 10 Bacterial Strains Isolated from Root Nodules of Alnus Trees in New Hampshire.

Here, we report the draft genome sequences obtained for 10 bacterial strains isolated from root nodules of trees. These members of the nodule microbiome were sequenced to determine their potential functional roles in plant health. The selected strains belong to the genera , , , , , and .

Actinorhizal Signaling Molecules: Root Hair Deforming Factor Shares Properties With NIN Inducing Factor.

Actinorhizal plants are able to establish a symbiotic relationship with bacteria leading to the formation of root nodules. The symbiotic interaction starts with the exchange of symbiotic signals in the soil between the plant and the bacteria. This molecular dialog involves signaling molecules that are responsible for the specific recognition of the plant host and its endosymbiont.

Draft genome sequence of the symbiotic Frankia sp. strain BMG5.30 isolated from root nodules of Coriaria myrtifolia in Tunisia.

Frankia sp. strain BMG5.30 was isolated from root nodules of a Coriaria myrtifolia seedling on soil collected in Tunisia and represents the second cluster 2 isolate.

Health Plans Can't Ignore The Customer Experience Any Longer.

With regulations limiting differentiation between products, health plans must rethink consumer experience to meet expectations of today's consumers, who seek convenience, quality, and speed from their health care organizations. Many plans understand they need to connect more effectively with their end customers, but technological, cultural, and other obstacles are in the way.

Permanent Draft Genome Sequences for sp. Strains LCM 4576, LCM 4577, and ORS3428, Salt-Tolerant, Nitrogen-Fixing Bacteria Isolated from Senegalese Soils.

The genus contains many species that are able to form nitrogen-fixing nodules on plants of the legume family. Here, we report the draft genome sequences for three strains. The genome sizes of strains LCM 4576, LCM 4577, and ORS3428 were 7.

Permanent Draft Genome sequence for sp strain CcI49, a Nitrogen-Fixing Bacterium Isolated from that Infects .

sp. strain CcI49 was isolated from nodules However the strain was unable to re-infect , but was able to infect other actinorhizal plants including . Here, we report the 9.

Permanent Draft Genome Sequence of Strain Hm, an Entomopathogenic Bacterium Isolated from Nematodes.

strain Hm is an entomopathogenic bacterium that forms a symbiotic association with nematodes. Here, we report a 5.0-Mbp draft genome sequence for strain Hm with a G+C content of 44.

Permanent draft genome sequence of sp. NRRL B-16219 reveals the presence of canonical genes, which are highly homologous to those detected in Frankia Dg1 genome.

sp. NRRL B-16219 was directly isolated from a soil sample obtained from the rhizosphere of growing in the USA. Its host plant range includes members of species.

Draft Genome Sequence of the Symbiotic Sp. Strain KB5 Isolated from Root Nodules of .

sp. strain KB5 was isolated from and previous studies have shown both nitrogenase and uptake hydrogenase activities under free-living conditions. Here, we report 5.

Permanent Draft Genome Sequence for sp. Strain Cc1.17, a Nitrogen-Fixing Actinobacterium Isolated from Root Nodules of .

sp. strain Cc1.17 is a member of the lineage 3, the organisms of which are able to reinfect plants of the Eleagnaceae, Rhamnaceae, and Myricaceae families and the genera and Here, we report the 8.

Permanent Draft Genome Sequence of sp. Strain LCM 4573, a Salt-Tolerant, Nitrogen-Fixing Bacterium Isolated from Senegalese Soils.

The genus contains many species that are able to form nitrogen-fixing nodules on plants of the legume family. Here, we report the 5.5-Mb draft genome sequence of the salt-tolerant sp.

Permanent Draft Genome Sequence of the French Bean Symbiont sp. Strain RSm-3 Isolated from the Eastern Himalayan Region of India.

The genus contains many species able to form nitrogen-fixing nodules on plants of the legume family. Here, we report the 6.9-Mbp draft genome sequence of sp.

Permanent Draft Genome Sequences of Three sp. Strains That Are Atypical, Noninfective, Ineffective Isolates.

Here, we present draft genome sequences for three atypical strains (lineage 4) that were isolated from root nodules but are unable to reinfect actinorhizal plants. The genome sizes of sp. strains EUN1h, BMG5.

Permanent Draft Genome Sequence of sp. Strain LCM 4579, a Salt-Tolerant, Nitrogen-Fixing Bacterium Isolated from Senegalese Soil.

The genus (formerly ) contains many species able to form nitrogen-fixing nodules on plants of the legume family. Here, we report the 6.1-Mb draft genome sequence of sp.

Permanent Draft Genome Sequence of Frankia sp. Strain AvcI1, a Nitrogen-Fixing Actinobacterium Isolated from the Root Nodules of Alnus viridis subsp. crispa Grown in Canada.

Frankia strain AvcI1, isolated from root nodules of Alnus viridis subsp. crispa, is a member of Frankia lineage Ia, which is able to reinfect plants of the Betulaceae and Myricaceae families. Here, we report a 7.

Permanent Draft Genome Sequence of Frankia sp. Strain ACN1ag, a Nitrogen-Fixing Actinobacterium Isolated from the Root Nodules of Alnus glutinosa.

Frankia strain ACN1(ag) is a member of Frankia lineage Ia, which are able to re-infect plants of the Betulaceae and Myricaceae families. Here, we report a 7.5-Mbp draft genome sequence with a G+C content of 72.

Cyclic mechanical strain of myocytes modifies CapZβ1 post translationally via PKCε.

The heart is exquisitely sensitive to mechanical stimuli and adapts to increased demands for work by enlarging the cardiomyocytes. In order to determine links between mechano-transduction mechanisms and hypertrophy, neonatal rat ventricular myocytes (NRVM) were subjected to physiologic strain for analysis of the dynamics of the actin capping protein, CapZ, and its post-translational modifications (PTM). CapZ binding rates were assessed after strain by fluorescence recovery after photobleaching (FRAP) of green fluorescent protein (GFP) expressed by a GFP-CapZβ1 adenovirus.

Comparison of clonidine, local anesthetics, and placebo for pain reduction in pediatric tonsillectomy.

Objective: To determine if pretonsillectomy injection of local anesthetics with and without clonidine reduces pain following tonsillectomy in children.

Design: A prospective, randomized, double-blind, placebo-controlled trial.

Setting: Tertiary care academic medical center.

Effects of raised-intensity phonation on inflammatory mediator gene expression in normal rabbit vocal fold.

Objective: To investigate the hypothesis that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory messenger RNA (mRNA) expression in vivo.

Study Design: Prospective animal study.

Setting: Laboratory.