Publications by authors named "Emily A Craig"
Benzo[]pyrene and phenanthrene hemoglobin adducts as biomarkers of longer-term air pollution exposure.
Environ Sci Process Impacts
January 2025
Article Synopsis
- The study examines PAH-hemoglobin adducts in blood samples from pregnant women in Rochester, NY, as potential long-term exposure biomarkers for air pollution.
- Researchers measured specific hydrolysis products of PAH-hemoglobin adducts (BaPT and PHET) and linked these to cumulative exposure to particulate matter (PM) during pregnancy.
- The results indicated positive correlations between these biomarker levels and PM exposure over specified gestational weeks, highlighting PAH-hemoglobin adducts as effective indicators of longer-term air pollution exposure, while no link was found with NO exposure.
Associations of Gestational Exposure to Air Pollution and Polycyclic Aromatic Hydrocarbons with Placental Inflammation.
Environ Health (Wash)
September 2024
Article Synopsis
- Restricted fetal growth (RFG) is linked to higher perinatal mortality and is associated with gestational exposure to various air pollutants like PM, NO, and PAHs.
- This study analyzed how air pollution exposure during different trimesters affects inflammatory markers in the placenta, involving a cohort of 263 pregnant women in Rochester, NY.
- Findings indicate that increased PM exposure in early pregnancy is linked to lower placental IL-6 levels, while higher PAH levels were associated with increased TNF-α levels at different stages, suggesting air pollution can change the placenta's inflammatory response at delivery.