Germline genetic variants in young-onset sporadic pituitary macroadenomas: A multigene panel analysis.

Mutations in several genes have been associated with familial forms of pituitary adenomas. Sporadic pituitary adenomas (i.e.

Long-term clinical sequelae and socio-professional performance in craniopharyngioma patients.

Background: Craniopharyngioma (CP) is a rare tumor, leading to several post-treatment sequelae which may have significant clinical and social implications, including impaired academic performance or employability.

Methods: We conducted a retrospective study involving CP patients followed at our center between 1986 and 2020. Data on demographics, clinical, imaging, and treatment characteristics were collected from the clinical records.

[Autoimmune thyroid disease: a case report].

Autoimmune thyroid disease is the most common cause of subclinical thyroid dysfunction (hypo and hyperthyroidism) in the western countries. Autoimmune thyroid diseases with clinical relevance (Graves' disease and autoimmune hypothyroidism) are common and can present with a large clinical and laboratorial spectrum. Hypo and hyperthyroidism can exist in the same patient, on different times.

[Assessment of an obesity clinic in a center hospital].

Introduction: Slight weight losses (5%) are consensually accepted as important in the treatment of obesity today. Some authors also consider that maintaining weight is an indicator of success in the treatment of this condition.

Objective: Characterisation and assessment of changes in weight in obese patients monitored at an obesity clinic in a hospital endocrinology department.