Publications by authors named "Elizabeth D Barrows"
Purpose: Among cancer predisposition genes, most direct-to-consumer (DTC) genetic tests evaluate three Ashkenazi Jewish (AJ) founder mutations in , which represent a small proportion of pathogenic or likely pathogenic variants (PLPV) in cancer predisposing genes. In this study, we investigate PLPV in and other cancer predisposition genes that are missed by testing only AJ founder mutations.
Methods: Individuals were referred to genetic testing for personal diagnoses of breast and/or ovarian cancer (clinical cohort) or were self-referred (nonindication-based cohort).
Article Synopsis
- Small cell lung cancer (SCLC) is a very serious type of lung cancer that is hard to treat and usually has a bad outcome.
- For a long time, the main treatment was chemotherapy with platinum and etoposide, which helped a bit but didn't last long.
- New studies showed that adding special medicines called immune checkpoint inhibitors, like atezolizumab and durvalumab, to chemotherapy can help patients live longer, even though many still don't do well.
Hyperkalemia is a common and an important cause of death in maintenance hemodialysis patients. Here we investigated the effect of patiromer, a synthetic cation exchanger, to regulate potassium homeostasis. Serum and stool electrolytes were measured in 27 anuric patients with hyperkalemia receiving hemodialysis (mainly 2 mEq/L dialysate) during consecutive two weeks of no-treatment, 12 weeks of treatment with patiromer (16.
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