Evaluation of a Fruit and Vegetable Voucher Program in a Prenatal and Pediatric Primary Care-Based Obesity Prevention Program.

Maternal consumption of fruits and vegetables can reduce future childhood obesity risk. , a fruit and vegetable voucher program redeemable at New York City (NYC) farmers' markets, supports access to fresh produce. In a cross-sectional analysis within a cohort study, we evaluated the integration of into the prenatal expansion of a primary care-based obesity prevention program.

Does missing trust lead to overuse or underuse of health care services?

Research about mistrust in health care often relies on the narrative that lacking trust causes underuse of health care services. This narrative seemed to hold up in the COVID-19 pandemic era, when mistrust in systems and providers led to widely recognized vaccine hesitancy and reluctance to seek care. In this review, we suggest that the "mistrust leads to underuse" narrative is important but incomplete, as mistrust in health care may also cause patients to overuse health care services.

Multi-ancestral origin of intestinal tumors: Impact on growth, progression, and drug efficacy.

Background: Data are steadily accruing that demonstrate that intestinal tumors are frequently derived from multiple founding cells, resulting in tumors comprised of distinct ancestral clones that might cooperate or alternatively compete, thereby potentially impacting different phases of the disease process.

Aim: We sought to determine whether tumors with a multi-ancestral architecture involving at least two distinct clones show increased tumor number, growth, progression, or resistance to drug intervention.

Methods: Mice carrying the Min allele of Apc were generated that were mosaic with only a subset of cells in the intestinal epithelium expressing an activated form of PI3K, a key regulatory kinase affecting several important cellular processes.