Synergistic antibacterial effects of postbiotics combined with linezolid and amikacin against nosocomial pathogens.

Background And Aim: The global rise in antimicrobial resistance (AMR) has rendered many conventional antibiotics less effective, particularly against nosocomial pathogens such as , , , and . This study investigated the antimicrobial and synergistic effects of postbiotics derived from , , , and , administered alone or in combination with either linezolid (for ) or amikacin (for Gram-negative strains).

Materials And Methods: Postbiotics were obtained through anaerobic fermentation, followed by centrifugation and filtration.