Correction to: ABCA7 and EphA1 Genes Polymorphisms in Late-Onset Alzheimer's Disease.

The original version of this article unfortunately contained a mistake in the Authorgroup section. Author Azra Delpak's given name was misspelled as "Azar".

Association of MS4A6A, CD33, and TREM2 gene polymorphisms with the late-onset Alzheimer's disease.

Alzheimer's disease (AD), which is a progressive neurodegenerative disorder, causes structural and functional brain disruption. MS4A6A, TREM2, and CD33 gene polymorphisms loci have been found to be associated with the pathobiology of late-onset AD (LOAD). In the present study, we tested the hypothesis of association of LOAD with rs983392, rs75932628, and rs3865444 polymorphisms in MS4A6A, TREM2, CD33 genes, respectively.

ABCA7 and EphA1 Genes Polymorphisms in Late-Onset Alzheimer's Disease.

Large-scale genome-wide studies have revealed the role of several genes and their respective single-nucleotide polymorphisms (SNPs) in the pathophysiology of late-onset Alzheimer's disease (LOAD). Here, the frequencies of ABCA7 SNPs rs3764650 and rs4147929 and EphA1 SNP rs11771145 were assessed and compared in LOAD patients and healthy subjects. In a case-control study, 110 patients with LOAD (case) and 88 healthy unrelated age- and gender-matched individuals (control), both from Azeri descent, were enrolled.

The use of mixer torque rheometry to study the effect of formulation variables on the properties of wet granulations.

Mixer torque rheometry was used to investigate the rheological behavior of wet granulations with different concentrations of drug, binder, and water. An experimental design was employed to systematically study the effects of the three formulation variables on the torque profiles of the wet masses over time. Under comparable conditions, increasing binder and water concentrations tended to produce higher wet mass consistencies.