Exercise-Induced Hypertension Is Associated With Gestational Hypertension Occurrence in Patients With Repaired Aortic Coarctation.

Background: Patients with repaired aortic coarctation (rCoA) are at risk of having exercise-induced hypertension (EIH) even with normal resting blood pressure (BP). A similar hypertensive response may occur during pregnancy, yet whether EIH is predictive of future gestational hypertension (GHTN) occurrence in rCoA patients is unknown.

Objectives: The aim of this study was to evaluate for an association between EIH and subsequent occurrence of GHTN in patients with rCoA with normal resting BP.

Social determinants of cardiovascular disease in women with and without breast cancer.

Purpose: Social determinants of health (SDOH) may impact cardiovascular (CV) risk in women with and without breast cancer (BC).

Methods: In 153,401 participants without prevalent CV disease from the Women's Health initiative (WHI), we assessed key SDOH factors: geographic region, rurality, insurance status, and household income. Multivariable Cox proportional hazards models were used to assess associations between SDOH factors and a composite CV outcome, which included incident myocardial infarction, incident stroke, hospitalization for heart failure, or CV death.

The Impact of Intravascular Ultrasound Use on 1-Year Outcomes After Infrapopliteal Endovascular Intervention.

Background: Data supporting the use of intravascular ultrasound (IVUS) in aortoiliac and femoropopliteal endovascular intervention are becoming increasingly robust, but data in the infrapopliteal circulation remain limited. The aim of this study was to evaluate the association between IVUS use and 1-year outcomes after infrapopliteal intervention.

Methods: All infrapopliteal endovascular interventions that occurred between 2018-2021 at a single academic medical center were retrospectively reviewed.

Successful treatment of immune checkpoint inhibitor-associated fulminant myocarditis with abatacept and ruxolitinib: a case report.

Background: Immune checkpoint inhibitors (ICIs) are a class of cancer immunotherapy with growing indications for treatment of various malignancies. Immune checkpoint inhibitors are monoclonal antibodies that block inhibitory pathways in immune cells, including cytotoxic T lymphocyte antigen-4 (CTLA4), programmed death 1 receptor (PD1), and programmed cell death ligand-1 (PDL1), to activate the immune system. However, these agents can disrupt self-tolerance and lead to immune-related adverse events.

Relationship between incident cardiovascular disease and quality of life after a breast cancer diagnosis.

Purpose: Breast cancer survivors are at risk for both poor quality of life (QoL) and cardiovascular disease (CVD). This study examines whether incident CVD after breast cancer independently predicts QoL.

Methods: Using data from the Women's Health Initiative, we included women who were diagnosed with invasive breast cancer during follow-up and free of prevalent CVD prior to breast cancer.

Life's Essential 8 and Incident Cardiovascular Disease in U.S. Women With Breast Cancer.

Background: Relationships between lifestyle risk factors and cardiovascular disease (CVD) risk in women with breast cancer (BC) are underexplored.

Objectives: To evaluate the incidence of CVD in relation to the Life's Essential 8 (LE8) score among women with BC.

Methods: Data from the Women's Health Initiative were utilized.

Get2PrEP2-A Provider Messaging Strategy to Improve PrEP Uptake: A Randomized Controlled Quality Improvement Project.

Introduction: HIV preexposure prophylaxis (PrEP), a key strategy for preventing HIV transmission, requires awareness and access to PrEP services. Although all patients should be made aware of HIV PrEP; the diagnosis of bacterial sexually transmitted infections (STIs) is an important indicator of potential HIV PrEP need. In a previous evaluation of Get2PrEP (G2P), we found that an electronic medical record laboratory comments did not increase the frequency of PrEP discussions between patients and providers.

A narrative review of heart failure with preserved ejection fraction in breast cancer survivors.

Advances in breast cancer (BC) treatment have contributed to improved survival, but BC survivors experience significant short-term and long-term cardiovascular mortality and morbidity, including an elevated risk of heart failure with preserved ejection fraction (HFpEF). Most research has focused on HF with reduced ejection fraction (HFrEF) after BC; however, recent studies suggest HFpEF is the more prevalent subtype after BC and is associated with substantial health burden. The increased HFpEF risk observed in BC survivors may be explained by treatment-related toxicity and by shared risk factors that heighten risk for both BC and HFpEF.