Glutaraldehyde-crosslinked chitosan-graft-poly(N-hydroxyethyl acrylamide) films: Synthesis, characterization, and application as Fe adsorbent.

This study aimed to develop CS-g-PHEAA-GA films (G1-G9) by grafting poly(N-hydroxyethyl acrylamide) (PHEAA) onto chitosan (CS) and crosslinking with glutaraldehyde (GA), in order to investigate their Fe-binding capacity and hemocompatibility. The resulting films were evaluated for grafting yield (G%), pH-dependent swelling kinetic (at pH 3.2, 5, 7.

Chitosan-graft-poly(N-hydroxy ethyl acrylamide) copolymers: Synthesis, characterization and preliminary blood compatibility in vitro.

Poly(N-hydroxy ethyl acrylamide) was grafted onto chitosan in aqueous acidic medium using potassium per sulphate initiator to obtain polymer surfaces with blood compatibility for potential biomedical applications. Thermally cross-linked products were obtained upon drying at 60 °C overnight. Chemically cross-linked films were prepared using methylene bis acrylamide (MBA) cross-linker.