National assessment of the feasibility and satisfaction of e-prescribing programmes in critical care units.

Introduction: Intensive Care Units (ICU) are recognized as high-risk settings for medication errors, primarily due to the complex pharmacological regimens and the critical condition of patients. It is estimated that the probability of errors occurring in these units is two to three times higher than in general hospital patients, with prescribing and administration being the stages most frequently associated with such incidents.

Objective: To evaluate the applicability and satisfaction with electronic prescribing systems in Intensive Care Units of hospitals in Spain.

[Cannabinoid content in seized hashish joints from Castilla y León (Spain)].

Background: Cannabis, in both its herbal form and resin-derived products, is the most widely consumed illicit drug worldwide. This study aimed to determine the potency and dosage of the primary cannabinoids present in cannabis resin from joints circulating in the region.

Methods: A descriptive study was conducted on seized joints confiscated by law enforcement agencies in the Autonomous Community of Castilla y León (Spain) between 2017 and 2020.

Experience With the Use of Paromomycin Via Nasogastric Tube as Treatment for Cryptosporidium Infection: A Case Report.

Cryptosporidiosis is an infectious disease caused by the Cryptosporidium parasite, primarily affecting the gastrointestinal tract of both humans and animals. Transmission occurs via fecal-oral route, mainly through ingestion of water or food contaminated with oocysts, the parasite's infectious form. Immunocompromised individuals are particularly susceptible to severe and prolonged symptoms.

Review of Drug Storage Conditions, A Case Report.

High temperatures during the summer season are a very important factor to be considered due to their possible influence on drug stability and effectiveness. This is especially important in those patients included in clinical trials, polymedicated or with long-term pharmacological therapies.

Determination of plasma uracil as a screening for dihydropyrimidine dehydrogenase deficiency: clinical application in oncological treatments.

Aims: Treatment with dihydropyrimidines poses a significant risk of serious adverse reactions for patients with dihydropyrimidine dehydrogenase (DPD) deficiency. This study seeks to analyse the correlation between DPD deficiency and plasmatic uracil values in patients who are candidates for a fluoropyrimidine scheme. It also studies the incidence of adverse events (AEs) in patients with DPD deficiency established with plasmatic uracil determination.

A guide for the administration of oral antineoplastic in patients with swallowing disorders.

Objective: To review the available literature on the administration of oral antineoplastic drugs in patients with swallowing disorders and  ystematize the information obtained.

Method: Between September 2019 and April 2020, two hospital  harmacists drew up a list of the oral antineoplastic drugs available in  Spain, which was then distributed to three hospital pharmacists, each of  whom carried out a literature search and a review. An analysis was made  of the prescribing information and searches were performed in Pubmed, Micromedex, Uptodate, the Cancer Care Ontario website,  different pharmaceutical bulletins, feeding tube administration guidelines,  and tertiary information sources.