Publications by authors named "Eduardo Jane"
Theranostic drugs represent an emerging path to deliver on the promise of precision medicine. However, bottlenecks remain in characterizing theranostic targets, identifying theranostic lead compounds, and tailoring theranostic drugs. To overcome these bottlenecks, we present the Theranostic Genome, the part of the human genome whose expression can be utilized to combine therapeutic and diagnostic applications.
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- Molecular medicine aims to understand diseases at the molecular level and apply this knowledge to create targeted diagnostics and therapies.
- The concept of the Imageable Genome is introduced, representing parts of the human genome detectable through molecular imaging, enhanced by a deep learning hybrid pipeline linking genes to imaging methods.
- Analyzing RNA-seq data from over 60,000 individuals identifies important imageable genes associated with various human diseases, paving the way for new imaging tools that enhance disease understanding and treatment.