Publications by authors named "Eduardo Botello"

Generative artificial intelligence (AI), particularly large language models (LLMs), has emerged as a transformative technology across all medical specialties, including musculoskeletal (MSK) oncology. These models, such as ChatGPT and others, can process natural language, synthesize vast amounts of information, and generate contextually relevant outputs that resemble human communication. In orthopedic oncology, LLMs show promise in facilitating literature reviews, enhancing patient education, and supporting clinical decision-making by analyzing multidimensional data while providing improved logic-based reasoning.

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Aims: Cancer care guidelines have been developed in many subspecialities, usually in advanced health systems. However, there are notable global disparities in healthcare access, which can impact sarcoma care. Unfortunately, there is a lack of global data on this subject.

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Purpose: Bone tumors around the hip pose significant surgical challenges. While surgical dislocation with a trochanteric flip osteotomy through a posterior approach is commonly used, it is associated with known complications. This study is the first to report outcomes using surgical hip dislocation without a trochanteric osteotomy for this purpose.

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Inappropriate or delayed initial management of musculoskeletal neoplasms can lead to severe consequences, emphasizing the need to define core competencies for frontline practitioners. Such competencies can guide medical education and residency training objectives. This study aimed to identify core clinical competencies required by general practitioners and general orthopedic surgeons without oncologic training for the initial management of musculoskeletal tumors, with a focus on implications for medical education.

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Aims: The Birmingham Orthopaedic Oncology Meeting (BOOM), held in January 2024, convened 309 delegates from 53 countries to discuss and refine 21 consensus statements on the optimal management of chondrosarcoma.

Methods: With representation from Europe (43%; n = 133), North America (17%; n = 53), South America (16%; n = 49), Asia (13%; n = 40), Australasia (5%; n = 16), the Middle East (4%; n = 12), and Africa (2%; n = 6), the combined experience of treating bone sarcomas among attendees totalled approximately 30,000 cases annually, equivalent to 66 years of experience in the UK alone. The meeting's process began with the formation of a local organizing committee, regional leads, and a scientific committee comprising representatives from 150 specialist units across 47 countries.

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The hindfoot is an uncommon site for malignant tumours. While limb salvage procedures are now more common for treating bone sarcoma, there is limited information available on hindfoot reconstruction alternatives because of its low incidence and its challenging outcomes. We present a case report of a man in his late 60s with synovial sarcoma affecting the right heel (calcaneus and soft tissue).

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Article Synopsis
  • Fragility pelvic fractures are becoming more common due to increased life expectancy, often requiring surgery with ilio-sacral screws for stabilization.* -
  • This review discusses a novel, low-cost cement augmentation technique for ilio-sacral screws, designed for patients with poor bone quality and includes case examples from five patients treated between 2017 and 2024.* -
  • The new surgical method is straightforward and uses readily available instruments, but further research is needed to prove its efficacy compared to traditional techniques without cement augmentation.*
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Introduction: Surgical procedures in contemporary practice frequently employ energy-based devices, yet comprehensive education surrounding their safety and effectiveness remains deficient. We propose an innovative course for residents that aims to provide basic electrosurgery knowledge and promote the safe use of these devices.

Methods: We developed a simulated training course for first-year general surgery and orthopedic residents.

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Article Synopsis
  • * The Birmingham Orthopaedic Oncology Meeting in January 2024 gathered 300 experts from over 50 countries to reach global consensus on chondrosarcoma treatment and address challenges related to periprosthetic joint infection in cancer surgeries.
  • * The meeting aimed to not only resolve current controversies but also to encourage collaboration among specialists for future research that could improve patient outcomes worldwide.
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Background: Osteoporosis increases the risk of periprosthetic fracture and loosening in hip arthroplasty. Many methods have been proposed to assess bone quality in X-rays, including both qualitative such as the Dorr classification and quantitative such as the Calcar-Canal Ratio (CCR) and Cortical-Thickness index/Canal-Bone ratio (CTI/CBR). The Canal-Diaphysis ratio (CDR) has been described as a predictor for hip fragility fractures; however, its relationship with bone mineral density (BMD) has not been described.

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Musculoskeletal tumors are uncommon. However, the true burden of all bone and soft tissue tumors of extremities is underestimated. Usually, the diagnosis of sarcomas is missed or delayed.

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Article Synopsis
  • The study aimed to compare various survival prognostic models for patients with metastatic bone disease in the long bones of a Chilean population.
  • This multicentric retrospective analysis involved reviewing the medical records of 136 surgically treated patients from 2016 to 2019, assessing predictive survival times using four specific scoring systems.
  • The findings indicated that the PathFx model was most accurate for 3 and 6-month predictions, while the IOR score was better for 12-month survival, with an overall 44% survival rate after one year.
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Introduction: Hip fracture patients have been severely affected by the COVID-19 pandemic; however, the sub acute effects of a concomitant SARS-CoV-2 infection and the outcomes in highly exposed developing countries are still unknown. Our objective is to describe the morbidity and mortality of elderly patients admitted for a hip fracture during the COVID-19 pandemic in Chile, with a minimum 90-day follow-up. Also, to elucidate predictors for mortality and to compare mortality results with the pre-pandemic era.

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Nasal and skin colonization by methicillin-resistant (MRSA) are linked to a higher incidence of infection after total joint replacement. The prevalence of colonization is poorly defined in Latin American countries. The aim of the present study was to determine the prevalence of MRSA colonization in the nostrils and groin using real-time polymerase chain reaction (RT-PCR) in patients undergoing total hip arthroplasty (THA).

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Introduction: Surgical instrument contamination during total joint replacement is a matter of major concern. Available recommendations suggest changing suction tips, gloves and avoiding light handle manipulation during the procedure. There is a paucity of data regarding surgical gown contamination.

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Background: As the population ages, patients exposed to osteoporotic fractures increase, especially hip fracture, which is the most severe and costly.

Aim: To characterize surgical practices in the management of hip fractures in older patients through a nationwide survey of specialized hip surgeons dedicated to the care of these patients.

Material And Methods: A survey composed of 32 questions was formulated, including demographic factors, preoperative evaluation, definitive treatment, and postoperative management.

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Background: The management of nondisplaced femoral neck fractures (FNFs) has evolved, with emphasis in radiographic features such as posterior displacement. However, the role of advanced imaging in this scenario is still not well defined. Therefore, our objective is to assess the impact of a computed tomography scan (CT) on interobserver agreement (IA) of fracture classification, posterior tilt measurement, and treatment decisions in nondisplaced FNF in elderly patients.

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The number of osteoporotic fractures is increasing along with population aging. Most patients with these type of fractures are older than 65 years, with multiple chronic conditions and different degrees of disability. Hip fracture is the most relevant osteoporotic fracture due to its frequency, costs, severity and complications.

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Cystic echinococcosis is a chronic parasitic zoonosis of high prevalence in Chile. We report a clinical case of a 66-year-old man, domiciled in an urban area of the Maule Region, who presents skeletal muscle cystic echinococcosis. Consultation for pain, volume increase and left thigh fistula that gives out crystalline fluid.

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Background: Surgical dislocation of the hip remains an important alternative in hip preservation surgery, especially when a dynamic access to the hip is needed and arthroscopy is not a suitable option. We describe a novel technique for operative dislocation of the hip without trochanteric osteotomy and the clinical results of our patients.

Methods: Surgical dislocation of the hip without trochanteric osteotomy was done through a modified lateral approach in all of the cases.

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Background: Distinguishing a benign enchondroma from a low-grade chondrosarcoma is a common diagnostic challenge for orthopaedic oncologists. Low interrater agreement has been observed for the diagnosis of cartilaginous neoplasms among radiologists and pathologists, but, to our knowledge, no study has evaluated inter- and intraobserver agreement among orthopaedic oncologists grading these lesions using initial clinical and imaging information. Determining such agreement is important since it reflects the certainty in the diagnosis by orthopaedic oncologists.

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Article Synopsis
  • * The study analyzed 228 patients aged 60 and older, finding that 80% were deficient and 18% were insufficient in vitamin D, particularly during the winter-spring seasons.
  • * Factors like higher health classification and age were related to vitamin D deficiency, but gender did not influence vitamin D levels.
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  • Total hip arthroplasty (THA) is a common and generally safe procedure, but periprosthetic infection (PPI) can be a serious complication, and the sources of the bacteria causing PPI are not fully understood.
  • The study examined 36 surgical light handles used during hip surgeries for bacterial contamination using various culture methods.
  • Results showed 50% of the light handles were contaminated, primarily with Staphylococcus epidermidis and Staphylococcus aureus, highlighting the potential risk of these handles as a source of infection in hip arthroplasty.
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Hip fractures in the elderly individuals are a complex problem. Our objective was to determine whether orthogeriatric treatment is effective in terms of reducing length of hospital stay, morbidity, and mortality of elderly patients with a hip fracture compared with orthopedic (traditional) treatment. From July 2009 to May 2011, patients older than 65 years with a hip fracture were followed prospectively.

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