Publications by authors named "Eduard Ilgiyaev"
: The COVID-19 pandemic markedly increased the number of patients with infection-related acute respiratory distress syndrome who required extracorporeal membrane oxygenation (ECMO) and multiple blood transfusions. This study aimed to assess a potential correlation between the daily rate of transfused blood products and the intensive care unit (ICU) outcome of ECMO-supported COVID-19 patients. : Data were retrieved from the electronic databases of three Israeli tertiary care centers.
View Article and Find Full Text PDFPredicting whether extracorporeal membrane oxygenation (ECMO) treatment duration affects prognosis is important both medically and economically. : We conducted a retrospective, multicenter study to better understand the outcomes of patients treated with veno-venous (VV) ECMO over a prolonged duration, analyzing data from the Israel ECMO registry. The study included all adult patients treated with VV-ECMO due to COVID-19-induced respiratory failure.
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- The study analyzed the use of extracorporeal membrane oxygenation (ECMO) in pregnant women experiencing severe respiratory or circulatory failure across 10 hospitals in Israel over three years.
- Out of 540,234 live births, only 28 obstetric patients (5.2 per 100,000 births) were treated with ECMO, primarily for hypoxic respiratory failure due to conditions like ARDS, with COVID-19 being a significant factor.
- Despite the low incidence, ECMO resulted in high survival rates for both mothers (89.3%) and babies (100%), with complications being rare.
In this retrospective multicenter observational study, we describe the Israeli experience with veno-venous extracorporeal membrane oxygenation (VV ECMO) for the treatment of COVID-19-induced severe adult respiratory distress syndrome (ARDS), in which ECMO cannulation was done while the patients were awake and spontaneously breathing without endotracheal tube, namely "awake ECMO." We enrolled all adult patients with severe ARDS due to COVID-19, treated with VV ECMO between March 1, 2020, and November 30, 2021, in which cannulation was done while the patient was awake and spontaneously breathing. During the study period, 365 COVID-19 ARDS patients were treated with VV ECMO.
View Article and Find Full Text PDFBACKGROUND Many patients experiencing acute coronary syndrome (ACS) present in cardiac arrest. Mechanical chest compressions are a common tool in cardiopulmonary resuscitation (CPR) and have their benefits as well as disadvantages and reported complications. In recent years, veno-arterial extracorporeal oxygenation membrane (VA-ECMO) has proven to be a promising tool in these circumstances and is now considered part of the treatment algorithm in emergent and refractory cases.
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- Atrial fibrillation is a common heart arrhythmia treated through ablation, a procedure that carries risks, including a rare but fatal complication known as atrio-esophageal fistula.
- Two patients, a 67-year-old man and a 64-year-old woman with preexisting health issues, developed this complication about six weeks after undergoing radiofrequency ablation and presented with severe symptoms that rapidly worsened.
- Prompt recognition of symptoms like fever, neurological deficits, and gastrointestinal bleeding is crucial, as untreated atrio-esophageal fistula can lead to death, and early diagnosis is essential for potential treatment interventions.
Article Synopsis
- The study aimed to investigate sex-based differences in outcomes for patients with acute ischemic stroke (AIS) who underwent recanalization treatments at a medical center in Israel between 2011 and 2020.
- Researchers analyzed data from 811 patients, finding that women had higher mean age and more severe conditions compared to men, but both sexes had similar outcomes despite women presenting with more risk factors.
- The study concluded that while women had more severe symptoms, there were no significant differences in outcomes between sexes, highlighting the importance of managing risk factors to reduce stroke-related issues for both genders.
Outcomes of Extracorporeal Membrane Oxygenation (ECMO) for COVID-19 Patients: A Multi-Institutional Analysis.
Vaccines (Basel)
January 2023
Article Synopsis
- The study analyzes data from COVID-19 patients in Israel who required veno-venous ECMO support, focusing on their characteristics and outcomes.
- It included 197 patients, revealing an overall mortality rate of 54%, with younger survivors (mean age 48) having fewer comorbidities compared to deceased patients (mean age 53).
- The study concludes that younger patients and early cannulation (within 4 days) could lead to better survival rates, while ischemic heart disease is associated with a worse prognosis.
The green man enigma: Unique presentation of toxicology in the emergency department.
J Am Coll Emerg Physicians Open
October 2021
Article Synopsis
- A case report discusses a hypertensive crisis triggered by the combination of amphetamine and Marwitt's Kidney Pills, leading to a variety of nonspecific symptoms like chest pain and abdominal distress.
- Diagnosis was complicated by unusual physical signs such as green urine and fingernails, but was clarified using point-of-care ultrasound, revealing acute cardiac and pulmonary issues.
- The patient's history indicated regular use of an over-the-counter drug in Thailand containing methylene blue, combined with past amphetamine use, which contributed to his acute health crisis.
Article Synopsis
- The study analyzed 100 adult patients with Guillain-Barré syndrome (GBS) from 2006 to 2018, finding that a significant 46.8% exhibited an axonal pattern in their EMG results.
- A majority (58%) of those who initially presented with mild symptoms experienced a deterioration in their condition, with several losing the ability to walk independently.
- The research concluded that a higher incidence of axonal GBS was observed in Israel compared to European and North American cohorts, and emphasized the need for prompt treatment following a GBS diagnosis due to the disease's progressive nature.
Article Synopsis
- A study was conducted to evaluate the safety and efficacy of thrombolytic treatment (IVTPA) in patients with wake-up acute ischemic strokes, based on their normal non-contrast brain CT scans.* -
- The retrospective analysis included 306 patients, with 27 having wake-up strokes; outcomes such as discharge rates and in-hospital mortality were comparable between the two groups.* -
- The results suggest it's safe to administer IVTPA to wake-up stroke patients, proposing that treatment eligibility might be extended beyond the usual 4.5 hours for those with normal brain scans after a witnessed stroke.*
Article Synopsis
- * Between 2015-2018, 66 examinations were conducted successfully on anesthetized patients using a specific technique, resulting in no complications.
- * The findings suggest that placing patients in a left decubital position facilitates smooth insertion of the TEE probe on the first attempt, and this method is recommended for future use.
Background: The role of routine active surveillance cultures (ASCs) in predicting consequent bloodstream infections is unclear.
Objectives: To determine prospectively whether routine screening ASCs obtained on admission to the intensive care unit (ICU) can predict the causative agent of subsequent bloodstream infections.
Methods: We prospectively studied a cohort of 100 mechanically ventilated patients admitted consecutively to a 16-bed ICU.
Effect of captopril treatment on recuperation from ischemia/reperfusion-induced acute renal injury.
Nephrol Dial Transplant
January 2012
Article Synopsis
- Ischemia/reperfusion leads to acute kidney injury (AKI) primarily through increased hypoxia, oxidative stress, inflammation, and activation of the renin-angiotensin system (RAS), prompting researchers to examine angiotensin-converting enzyme (ACE) inhibition's effects on AKI progression in a rat model.
- In the study, rats underwent ischemia/reperfusion and were treated with varying doses of captopril to assess its impact on renal function and associated biomarkers, with evaluations occurring after different time points post-treatment.
- Results showed that captopril effectively reduced angiotensin-II levels and renal inflammation during the acute phase of AKI, enhancing kidney function and preserving tissue structure, although later phases revealed a
Article Synopsis
- - The study explored how sex differences impact survival rates in older patients with heart failure (HF), examining a range of clinical factors over a follow-up period of up to 5 years.
- - 162 females and 200 males were included, with survival rates showing 52.4% for females and 59% for males; factors like advanced age and renal dysfunction negatively affected survival for both sexes.
- - Specific risks were identified: for females, admission for pulmonary edema and high furosemide dosage were linked to lower survival, while for males, hypokalemia and hypocalcemia were significant; ultimately, renal dysfunction was a critical factor for both.