The rate of revision surgery for secondary deformities of the lip in cleft lip patients: A systematic review.

Introduction: Secondary deformities following primary cleft lip repair require varying degrees of surgical intervention, from minor scar revision to complete takedown and repair. Revision surgery can itself necessitate multiple interventions, representing a considerable burden for both patients and the health system. In this study, we evaluate the reported rates of revision surgery for secondary deformities of the lip within the literature.

A Novel Treatment of Hidradenitis Suppurativa With Radical Unroofing and Deepithelialization.

Hidradenitis suppurativa (HS) is a chronic inflammatory disease beginning with hyperkeratosis of the hair follicles in the dermis and leading to inflammation involving adjacent apocrine glands. HS has significant functional and psychological sequelae, but there is currently no standardized algorithm for treatment. For more severe cases of HS, wide surgical excision remains a standard method of treatment to address the underlying fibrosis and sinus tract formation.

Regional variations in cleft lip and palate repair techniques: A mixed-methods study of international volunteer surgeons.

Background: Despite the availability of multitudes of surgical techniques for cleft lip and/or palate (CLP) repair, the geographic distribution of their usage remains largely unknown. We investigated the technical preferences in CLP repair within an international cohort of volunteer surgeons.

Methods: This was a mixed-methods study.

The Rate of Secondary Speech Surgery After Cleft Palate Repair: A Systematic Review.

Background: Reported rates of velopharyngeal insufficiency (VPI) after primary palatoplasty for cleft palate (CP) range from 5% to 30%. Although some cases are managed with speech therapy, many patients with VPI require surgical intervention. In this study, we investigate the rate of VPI surgery in patients with CP.

Comparison of Lip Revision Rates in Traditional Versus Early Cleft Lip Repair: An Institutional Review.

Background: Traditional cleft lip repair (TLR) is performed between 3 and 6 months of age. For over 10 years, our institution has transitioned from offering presurgical nasoalveolar molding (NAM) before cleft lip repair to performing early cleft lip repair (ECLR) within 2 to 5 weeks of life, circumventing the use of NAM.

Purpose: This study aimed to estimate and compare the lip revision rates between patients who underwent ECLR versus TLR ± NAM.

A Regional Analysis of Diversity, Equity, and Inclusion Initiatives in Plastic Surgery Residency Programs.

Background: Residents seek inclusive training environments that prioritize diversity. To evaluate programs that focus on these elements, websites have become essential for applicants but often lack in diversity, equity, and inclusion (DEI) content. Thus, this study aimed to assess current efforts and attention to DEI within plastic surgery residency programs and compare them by region.

Polysomnogram Findings and Psychosocial and Academic Concerns in Children With Cleft Palate With or Without Cleft Lip.

Children born with a cleft palate with or without a cleft lip (CP±L) are at risk for sleep-disordered breathing, particularly obstructive sleep apnea (OSA). While OSA and CP±L have both been associated with higher risk for psychosocial and academic concerns, their combined risk has been understudied. This paper aimed to describe polysomnography findings and psychosocial and academic concerns among children with isolated (iCP±L) and syndrome-associated (sCP±L) clefts who had undergone primary palatoplasty.

Inpatient versus Outpatient Alveolar Bone Grafting: A Nationwide Cost Analysis.

ObjectiveTo compare postoperative outcomes and costs between inpatient and outpatient ABG in the United States.DesignRetrospective cohort.SettingMulti-institutional/national.

A Review of Socioeconomic Disparities in Submucous Cleft Diagnosis and Outcomes.

Submucous cleft palate (SMCP) is a common congenital anomaly characterized by a diastasis of the levator veli palitini muscle. The subtlety of SMCP on physical examination can contribute to diagnostic delays. This study aims to analyze the factors contributing to delays in care and subsequent postoperative outcomes in patients with SMCP.

Failure Rates Based on Alveolar Cleft Volume: Analysis of the Critical-Size Defect for Alveolar Bone Grafting.

Background: Alveolar bone grafting (ABG) using iliac crest bone graft (ICBG) is the best practice for children with complete cleft lip and palate. With the advent of recombinant human bone morphogenetic protein (rhBMP-2) and demineralized bone matrix (DBM), excellent results can be achieved while avoiding donor-site morbidity. This study aimed to determine critical-size defects by analyzing graft failure rates for ICBG and rhBMP-2/DBM to guide surgeons performing ABG.

A Single Institution 19 Year Comparison of Furlow and Straight Line Palatoplasty Techniques in Bilateral Cleft Lip and Palate.

Objective: This study aims to compare patients' speech correcting surgery and fistula rates between the Furlow and Straight Line (SLR) palatoplasty techniques when combined with greater palatine flaps for complete bilateral cleft lip and palate (BCLP) repair.

Design: This was a single-center IRB approved retrospective cohort study.

Setting: This study took place at an urban tertiary academic center.

A 10-Year Nationwide Analysis of Risk Factors of Readmission and the Implications of Same-Day Discharge Following Velopharyngeal Insufficiency Correcting Surgery.

ObjectiveTo investigate risk factors for readmission and the implications of same-day discharge for surgical management of velopharyngeal insufficiency (VPI).DesignRetrospective cohort.SettingMulti-institutional/national.

Dental Protraction Versus Surgery for Cleft Lip and Palate: A Budget Impact Analysis.

Class III malocclusion for individuals with cleft lip and palate has historically been managed with surgery. Orthodontic protraction is a noninvasive alternative that may be associated with lower costs. This analysis investigated the budget impact of protraction versus surgery from an institutional perspective.

Green-Solvent-Processed High-Performance Broadband Organic Photodetectors.

Solution-processed organic photodetectors with broadband activity have been demonstrated with an environmentally benign solvent, -xylene (-xylene), as the processing solvent. The organic photodetectors employ a wide band gap polymer donor PBDB-T and a narrow band gap small-molecule non-fullerene acceptor CO1-4F, both dissolvable in -xylene at a controlled temperature. The -xylene-processed devices have shown external quantum efficiency of up to 70%, surpassing the counterpart processed with chlorobenzene.

Early Ophthalmology Findings in Nonsyndromic Craniosynostosis.

Craniosynostosis (CS) occurs 1 in 2500 births and surgical intervention is indicated partly due to risk for elevated intracranial pressure (EICP). Ophthalmological examinations help identify EICP and additional vision concerns. This study describes preoperative and postoperative ophthalmic findings in CS patients (N=314) from chart review.

Microcarrier-Based Culture of Human Pluripotent Stem-Cell-Derived Retinal Pigmented Epithelium.

Dry age-related macular degeneration (AMD) is estimated to impact nearly 300 million individuals globally by 2040. While no treatment options are currently available, multiple clinical trials investigating retinal pigmented epithelial cells derived from human pluripotent stem cells (hPSC-RPE) as a cellular replacement therapeutic are currently underway. It has been estimated that a production capacity of >109 RPE cells annually would be required to treat the afflicted population, but current manufacturing protocols are limited, being labor-intensive and time-consuming.