Publications by authors named "Dorottya Gergo"
Purpose: Radiation exposure is a well-recognized occupational hazard for catheterization lab personnel. However, the extent of exposure disparities among different staff roles remains unclear. Existing research primarily focuses on primary operators, leaving a gap in understanding radiation risks for ancillary staff.
View Article and Find Full Text PDF: Nausea and vomiting frequently occur during postoperative recovery, chemotherapy, and pregnancy. While peppermint oil is traditionally used to relieve these symptoms, its efficacy remains uncertain. This systematic review and meta-analysis evaluates the efficacy of peppermint oil inhalation for postoperative (PONV), chemotherapy-induced (CINV), and pregnancy-related nausea and vomiting (NVP).
View Article and Find Full Text PDF: Gastrointestinal endoscopy is crucial for diagnosing colorectal cancer and inflammatory bowel diseases, but its effectiveness can be impacted by peristalsis, poor bowel preparation, and inadequate withdrawal time. Conventional antispasmodics, though effective, may not be suitable for elderly patients or those with comorbidities. L-menthol, derived from peppermint oil, has emerged as a safer alternative.
View Article and Find Full Text PDFBackground: The role of autoimmune beta-cell damage in cystic fibrosis-related glucose abnormalities remains unclear. This study evaluates the prevalence of pancreatic islet autoantibodies (AABs) by glycemic status and age, and assesses the risk of developing cystic fibrosis-related diabetes (CFRD) in people with cystic fibrosis (pwCF).
Methods: A random-effects meta-analysis examined AABs against glutamic acid decarboxylase (GADA), insulin (IAA), islet cell (ICA), islet antigen-2 (IA-2A) and zinc transporter 8 (ZnT8A) in pwCF (CRD42023482663).
Background: Timely management of sepsis with early targeted antimicrobial therapy improves patient outcomes. Rapid molecular assays (RMAs) have emerged, enabling the detection of bloodstream infection (BSI) with a shorter turnaround time than blood cultures (BCs). The accuracy of several RMAs has not been comprehensively reviewed.
View Article and Find Full Text PDFBackground: Accurate detection of kidney damage is key to preventing renal failure, and identifying biomarkers is essential for this purpose. We aimed to assess the accuracy of miRNAs as diagnostic tools for chronic kidney disease (CKD).
Methods: We thoroughly searched five databases (MEDLINE, Web of Science, Embase, Scopus, and CENTRAL) and performed a meta-analysis using R software.
The effectiveness of psychological interventions (PI) for malignant diseases is controversial. We aimed to investigate the effect of PI on survival and quality of life (QoL) in patients with cancer. We performed a systematic search of MEDLINE, Cochrane, and Embase databases to identify randomized controlled trials comparing PI to standard care (PROSPERO registration number CRD42021282327).
View Article and Find Full Text PDFBackground: Spasticity affects 54% of multiple sclerosis (MS) patients at disease onset, but this rate gradually increases with disease progression. Spasticity does not fully respond to standard treatment in one-third of the patients.
Objective: Our systematic review and meta-analysis assessed whether add-on nabiximols, can improve MS-associated refractory spasticity.
Factors influencing successful reconstruction of tympanic membrane perforations: a systematic review and meta-analysis.
Eur Arch Otorhinolaryngol
June 2023
Purpose: Based on a systematic review and meta-analysis, our study aimed to provide information about the factors that influence the success of tympanic membrane reconstruction.
Methods: Our systematic search was conducted on November 24, 2021, using the CENTRAL, Embase, and MEDLINE databases. Observational studies with a minimum of 12 months of follow-up on type I tympanoplasty or myringoplasty were included, while non-English articles, patients with cholesteatoma or specific inflammatory diseases, and ossiculoplasty cases were excluded.
Article Synopsis
- Cardiac cell lines (H9C2, AC16, HL-1) were systematically compared to primary cardiomyocytes and mature cardiac tissues to assess their characteristics and limitations in cardiovascular research.
- Findings revealed that cardiac cell lines exhibited significantly lower expression of cardiac markers and less pronounced cardiac phenotypes compared to primary and mature cells, even after differentiation.
- The study concludes that the low resemblance of cell lines to mature cardiac tissue limits their usefulness in research, highlighting the need to consider their translational value when selecting models for cardiomyocyte studies.
Article Synopsis
- * Researchers used a mouse model to analyze the expression of genes related to inflammation, fibrosis, and cholesterol metabolism, finding significant differences in the levels of certain proteins and inflammatory markers between sexes during NASH development.
- * Results indicate that while both sexes experience similar liver fat accumulation (steatosis), males show more fibrosis, with notable sex-specific differences in the inflammatory response and cholesterol metabolism, suggesting these factors contribute to the distinct progression of NASH in males and females.