Publications by authors named "Dorota Sentkowska"
Article Synopsis
- The study focuses on a specific bacterial species that can cause opportunistic infections in humans, making it a useful model for understanding how bacteria can switch from living harmlessly to becoming pathogenic.
- Researchers conducted a comprehensive analysis of the genomic sequences of seven bacterial isolates, discovering a complex structure with several extrachromosomal elements, including a new type of mobile genetic element.
- Key findings include the identification of unique virulence genes, notably the URE gene cluster related to ureolytic activity, highlighting the significance of the flexible genome in influencing the bacterium's ability to cause infections.
Differential Localization and Functional Specialization of Centromere-Like Sites in Replicons of .
Appl Environ Microbiol
April 2022
Partitioning systems ensure the stable inheritance of bacterial low-copy-number replicons, such as chromosomes, chromids, and megaplasmids. These loci consist of two genes encoding partition proteins A and B, and at least one centromere-like sequence. In chromids and megaplasmids, partitioning systems are often located in the vicinity of replication systems.
View Article and Find Full Text PDFBacteria of the genus are common components of the microbiomes of many naturally- and anthropogenically shaped environments. One species, , is unique within the genus because it is associated with opportunistic human infections. Therefore, strains of may serve as an interesting model to study the transition from a saprophytic to a pathogenic lifestyle in environmental bacteria.
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