Quantitative Analysis of Disc-Condyle Movement Following Disc Repositioning Operation By Arthroscopic for Bi-ADD Patients.

Background: This study aimed to assess the location of disc and the movement characteristic of disc-condyle following disc repositioning operation by bilateral arthroscopic (Bi-ADRO).

Methods: The consecutive patients enrolled, who received magnetic resonance imaging (MRI), 84 patients were included. 31 patients distributing in group N diagnosed as non-ADD.

Biomaterial-enhanced delivery of stem cell-derived exosomes for skin inflammatory diseases: Mechanisms and therapeutic advances.

Inflammatory skin diseases such as psoriasis, atopic dermatitis, vitiligo, and lupus erythematosus present persistent therapeutic challenges due to their chronic nature, immune dysregulation, and suboptimal treatment outcomes. Stem cell-derived exosomes have emerged as a promising cell-free therapeutic approach, capable of modulating immune responses, promoting tissue regeneration, and restoring skin homeostasis. This review provides a comprehensive overview of exosomes derived from various stem cell sources-including adipose tissue, bone marrow, umbilical cord, dental pulp, and induced pluripotent stem cells-and their roles in regulating immune cell function and facilitating skin repair.

Interplay between tunneling nanotubes and Wnt Signaling: Insights into cytoskeletal regulation and therapeutic potential.

Tunneling nanotubes (TNTs) are membranous structures that enable direct intercellular transfer of mitochondria, proteins, RNAs, and signaling molecules, playing key roles in tissue repair, immune coordination, and stress adaptation. Among their critical functions, TNT-mediated mitochondrial transfer rescues metabolically impaired cells, yet the regulatory mechanisms governing TNT formation and function remain incompletely understood. Recent studies highlight the Wnt signaling pathway-a conserved regulator of cell fate, polarity, and cytoskeletal remodeling-as a central modulator of TNT dynamics.

An intensive education program for caregivers ameliorates anxiety, depression, and quality of life in patients with drug-resistant temporal lobe epilepsy and mesial temporal sclerosis who underwent cortico-amygdalohippocampectomy.

This study aimed to investigate the effect of a caregiver intensive education program (CIEP) on anxiety, depression, and quality of life (QOL) in patients with drug-resistant temporal lobe epilepsy and mesial temporal sclerosis (TLE-MTS) who underwent cortico-amygdalohippocampectomy (CAH). Ninety patients with drug-resistant TLE-MTS who underwent CAH and their caregivers were recruited and randomly allocated to the CIEP group or control group as 1:1 ratio. Caregivers received the CIEP program or routine guidance/education (control group).