Publications by authors named "Dong-Won Lee"

Background/objectives: Burn injuries are a major public health concern. This study estimated global, regional, and national burn burdens by total body surface area from 1990 to 2021 and projected trends to 2050.

Methods: Utilizing data from the Global Burden of Disease Study 2021, we examined the prevalence, mortality, and years lived with disability (YLDs) according to age, sex, and region.

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Background: This study aimed to evaluate the feasibility and effectiveness of indocyanine green (ICG) angiography in transoral robotic thyroidectomy (TORT).

Methods: A total of 130 patients with papillary thyroid carcinoma who underwent TORT with ICG angiography (ICG group, 65 patients) and without ICG angiography (control group, 65 patients) were analyzed.

Results: The parathyroid detection rate did not differ between the control and ICG groups.

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Background: Syncope is a temporary loss of consciousness due to cerebral hypoperfusion associated with autonomic dysfunction. Vasovagal syncope (VVS) and postural orthostatic tachycardia syndrome (POTS) are the most common causes of syncope in adolescents.

Purpose: Here we conducted a comparative analysis of VVS and POTS in adolescents using transcranial doppler (TCD) and autonomic function tests to identify the mechanisms underlying the occurrence of each.

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PurposeThe purpose of this study was to compare the effectiveness and safety of drug eluting stents with percutaneous transluminal angioplasty and bare-metal stents in below the knee peripheral artery disease. : The systematic review was registered in Research Registry. A literature search was performed across four databases: PubMed, Medline/Embase, Cochrane Review, and Web of Science for eligible comparative studies.

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Introduction: Sexual health concerns are prevalent in breast cancer patients, yet are difficult to address given the stigma, sensitivity, and cultural differences. This study aims to assess the impact of culture on Sexual Well-being after autologous breast reconstruction (ABR) by examining three different countries from different continents: South Korea for Asia, Netherlands for Europe, and United States of America (USA) for North America.

Methods: Patients who underwent autologous (ABR) breast reconstruction between 2016 and 2022 and completed at least one BREAST-Q Sexual Well-being either preoperative and/or up to 2-year postoperative were included.

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Multiple sclerosis (MS) is an autoimmune disease characterized by the loss of oligodendrocytes (OLs) and axon demyelination in the central nervous system. Most therapeutic agents focus on regulating the immune response by suppressing autoimmune reactions. Therefore, developing therapeutic agents that promote remyelination by OLs at disease sites that have already undergone demyelination is necessary.

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Purpose: This study evaluated voice and swallowing outcomes following thyroidectomy by using the gasless transaxillary (GTAA) and transoral (TOA) approaches compared with the conventional transcervical approach (CTA).

Methods: A comprehensive search of the PubMed, EMBASE, and Cochrane Library databases was conducted through September 2024. Network meta-analyses were performed on 14 comparative studies, encompassing 1723 patients.

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This study presents a rare case of bilateral renal abscess caused by Aspergillus fumigatus in a 50-year-old male patient who underwent lung transplant for interstitial lung disease. The abscess developed as an opportunistic fungal infection as a result of immunosuppression from posttransplant therapy. Imaging studies revealed abscesses in both kidneys.

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Objectives: Effective treatment of laryngeal cancer requires clinical decision-making that balances survival outcomes with the preservation of essential functions, such as voice and swallowing. This study, led by the Clinical Practice Guideline Committee of the Korean Society of Head and Neck Surgery, aims to establish evidence-based recommendations to guide surgeons in optimizing treatment decisions for patients with laryngeal cancer.

Methods: A literature search was performed in the PubMed, Embase, Cochrane Library, and KoreaMed databases by a literature search expert and subsequently reviewed by a panel of 39 committee experts.

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To investigate the relationship between depression and AD, water avoidance stress (WAS) was induced for 10 days in both Tg2576 mice and wild-type (WT) mice. After WAS, memory function and depressive-like behavior were investigated in Tg2576 mice. Tg2576 WAS mice exhibited more depressive-like behaviors than WT WAS and Tg2576 control (CON) mice.

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 Prepectoral direct-to-implant (DTI) is a common implant-based breast reconstruction method used for patients with breast cancer, although patients often present capsular contracture as a common complication. This study aimed to investigate the causes and surgical outcomes of capsular contractures in patients with breast cancer who underwent prepectoral DTI.  The medical records of 392 patients (472 breasts) who underwent prepectoral DTI between August 2019 and July 2022 were retrospectively reviewed.

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Acute kidney injury (AKI) is a major but often underestimated risk factor for the development of chronic kidney disease (CKD). Exploring innovative approaches to prevent this progression is critical. Intermittent fasting (IF), recognized for its metabolic and anti-inflammatory benefits, may offer protective effects in this context.

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Metabolic syndrome (MetS) is a cluster of interrelated risk factors, including insulin resistance, hypertension, dyslipidemia, and visceral adiposity, all of which contribute to kidney microvascular injury and the progression of chronic kidney disease (CKD). However, the specific impact of each component of MetS on kidney microcirculation remains unclear. Given the increasing prevalence of obesity, understanding how visceral fat-particularly fat surrounding the kidneys-affects kidney microcirculation is critical.

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This study aimed to evaluate the current practices and trends of intraoperative facial nerve (FN) monitoring (IOFNM) during parotidectomy. A questionnaire containing 33 questions collecting information on the usage, indications, settings, techniques, loss of signal (LOS) management, anesthesiologist cooperation, and perception of usefulness of IOFNM was distributed among 348 members of the Korean Society of Head and Neck Surgery (KSHNS) via a dedicated website. The response rate was approximately 25.

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Article Synopsis
  • - Diabetic peripheral neuropathy (DPN) is a nerve disorder linked to diabetes, caused by high blood sugar and insulin signaling issues, which impact nutrient processing and nerve maintenance.
  • - Research aimed to create a zebrafish model for DPN to test drug effects on sensory nerve damage, utilizing a special system for targeted pancreatic cell destruction.
  • - Findings indicated that DPN is primarily due to loss of insulin receptor signaling rather than just high glucose levels, as nerve fibers were impaired but some cellular characteristics remained normal.
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This study presents an organocatalytic C-H functionalization approach for postpolymerization modification (PPM) of poly(ethylene oxide) (PEO). Most of PEO PPM is previously processed at the end hydroxy group, but recent advances in C-H functionalization open a way to modify the backbone position. Structurally diverse carboxylic acids are attached to PEO through a cascade process of radical generation by peroxide and oxidation to oxocarbenium by tertiary butylammonium iodide.

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Background: Focal segmental glomerulosclerosis (FSGS) is a notable subtype of glomerulonephritis in kidney transplantation, often resulting in graft failure. Yet, research comparing transplant outcomes between de novo and recurrent FSGS is scarce. This study aims to compare clinical features and transplant outcomes between these two categories.

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Article Synopsis
  • - A patient with autosomal dominant polycystic kidney disease experienced transplant renal artery stenosis after receiving a kidney from a deceased donor due to rotation and compression of the transplanted organ.
  • - The stenosis was linked to the patient's preexisting condition, which affected the positioning of the transplanted kidney.
  • - Surgical removal of the native polycystic kidney successfully resolved the stenosis and improved the function of the transplanted kidney, emphasizing the need for careful monitoring for renal artery stenosis after kidney transplants.
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Ischemia-reperfusion injury (IRI) in the kidneys is a major cause of acute kidney injury (AKI). Time-restricted feeding (TRF), known for its metabolic health benefits and alleviation of various chronic diseases without calorie restriction, was investigated for its potential protective effects against IRI-induced AKI. Male C57BL/6 mice underwent unilateral IRI, with their kidneys collected after two days.

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Article Synopsis
  • Time-restricted feeding (TRF) is a way of eating that improves health without needing to cut calories, and this study looks at its effects on kidney damage.
  • In the experiment, mice were fed in an 8-hour window each day before being given a substance that causes kidney injury.
  • Results showed that mice on TRF had less kidney damage and inflammation compared to those who didn't follow the TRF diet, suggesting that TRF might help protect kidneys from injury.
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is commonly found in the airway and is associated with airway inflammatory diseases. Zinc oxide (ZO) is known to be an essential microelement that facilitates fungal survival, growth, and proliferation. This study aimed to investigate the impact of ZO on -induced fungal sinusitis in rabbits.

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The integration of artificial intelligence (AI) and machine learning (ML) in healthcare has become a major point of interest and raises the question of its impact on the emergency department (ED) triaging process. AI's capacity to emulate human cognitive processes coupled with advancements in computing has shown positive outcomes in various aspects of healthcare but little is known about the use of AI in triaging patients in ED. AI algorithms may allow for earlier diagnosis and intervention; however, overconfident answers may present dangers to patients.

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Article Synopsis
  • Obesity is a big health problem that can make kidney injuries worse, especially when a person has had low blood flow to the kidneys (called ischemia-reperfusion injury).
  • In a study using mice, those on a high-fat diet had more kidney damage compared to those on a normal diet after going through this injury.
  • The results suggest that fat around the kidneys becomes unhealthy and causes more problems when combined with a high-fat diet, which means new treatments might be needed for obese people with kidney issues.
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