Publications by authors named "Dmitrii Shestakov"
Sarcopenia, the progressive loss of skeletal muscle mass and function with age, significantly contributes to frailty and mortality in older adults. Notably, muscles do not age uniformly-some retain structure and strength well into old age. This review explores the mechanisms underlying differential resistance to muscle aging, with a focus on sarcopenia-resistant muscles.
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- The extraocular muscles (EOMs) are distinct from other skeletal muscles due to their remarkable resistance to muscular dystrophies and aging, making them unique in their ability to maintain function.
- EOMs have complex structural properties, including diverse fiber types and specialized innervation, which contribute to their ability to execute rapid and precise eye movements.
- Research into EOMs may provide valuable insights for developing treatments for other skeletal muscle disorders, as understanding their cellular and molecular resilience could inform therapeutic strategies.