Publications by authors named "Ding-Ding Cui"

Objectives: To investigate the clinical characteristics and prognosis of acute erythroleukemia (AEL) in children.

Methods: A retrospective analysis was conducted on the clinical data, treatment, and prognosis of 8 children with AEL treated at the First Affiliated Hospital of Zhengzhou University from January 2013 to December 2023.

Results: Among the 7 patients with complete bone marrow morphological analysis, 4 exhibited trilineage dysplasia, with a 100% incidence of erythroid dysplasia (7/7), a 71% incidence of myeloid dysplasia (5/7), and a 57% incidence of megakaryocytic dysplasia (4/7).

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Article Synopsis
  • A study explored the characteristics and outcomes of childhood acute lymphoblastic leukemia (ALL) cases with specific gene mutations, involving 14 patients over 7 years.
  • The majority of affected children were girls, with a median age of just over 4 years, and they exhibited a high rate of complete remission (79%) after initial treatment but a notable recurrence rate of 21%.
  • Despite challenges, many children achieved long-term survival, and the overall 5-year survival rate for the group was an encouraging 92%.
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