Publications by authors named "Dinesh Chandra Agrawal"

Andrographolide (Andro), the major constituent of , is was known to reduces inflammatory reaction. In the current study, the ability of Andro to reduce pain sensation in a rat post-operative wound model was explored. The hind paws of 18 Sprague-Dawley rats (SD) bearing post-operative wounds received the following three treatments: Saline, Andro via direct injection into the paw (Andro-injected) and Tablet containing Andro + poly (lactic-co-glycolic acid) (PLGA) (Andro-tablet).

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Sacha inchi is a source of quality commercial oil in Taiwan. Oil extraction results in sacha inchi residue have not been utilized and not much investigated. Different edible seeds and nuts have different levels of nutrients.

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Investigations were carried out to study the effects of light-emitting diode (LED) lights on growth and development of isosteroidal alkaloids in embryogenic calli of D. Don, an important traditional Chinese medicine herb. Calli were cultured in glass bottles, each containing 100 mL of Murashige and Skoog's basal medium supplemented with 2% sucrose and 0.

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Background: Fritillaria cirrhosa, an important Chinese medicinal herb, is a Class-III protected and highly exploited species by pharmaceutical industry. Dwindling wild populations of species are unable to meet market demand. Therefore, this study was carried out to develop an in vitro propagation method for bulblet production.

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Article Synopsis
  • Andrographolide (Andro), an anti-inflammatory compound from Andrographis paniculata, was tested for its effectiveness in reducing pain sensitivity (allodynia) in a nerve injury model using male BalbC mice.
  • Mice were divided into four groups: a control group, a saline group, an Andro treatment group, and a non-steroidal anti-inflammatory drugs (NSAIDS) group, with pain responses measured after treatment.
  • Results showed that Andro significantly reduced pain sensitivity compared to both the saline and NSAIDS groups, correlating with lower levels of inflammatory cytokines in the spinal cord, indicating its potential for improved pain management.
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Ethnopharmacological Relevance: Kaempferitrin is extracted in significantly high quantities from the leaves of Cinnamomum osmophloeum (C.O) and Bauhinia forficata, and are used as an antidiabetic herbal remedy in China and Brazil. Commercial product using dry Cinnamomum osmophloeum leaves has been sold locally in Taiwan.

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Background: Peucedanum japonicum Thunb, an important medicinal herb is reported to possess pharmacological properties such as anti-obesity, anti-oxidant, anti-inflammatory, anti-bacterial, anti-diabetic and anti-platelet aggregation. The present study aimed to develop an in vitro plant regeneration system of P. japonicum via somatic embryogenesis and to analyse chlorogenic acid and rutin contents in a few commercially available plant products of P.

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Background: Saussurea involucrata (Kar. et Kir.) commonly known as 'snow lotus' or 'Xue Lian' is an important plant in the traditional Chinese system of medicine.

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Background: Gentiana scabra Bunge commonly known as 'Long dan cao' in China has been used in traditional Chinese medicines for more than 2000 years. Dry roots and rhizome of the herb have been used for the treatment of inflammation, anorexia, indigestion and gastric infections. Iridoids and secoiridoids are the main bioactive compounds which attribute to the pharmacological properties of this plant.

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Background: Glossogyne tenuifolia Cassini (Hsiang-Ju in Chinese) is a perennial herb native to Penghu Islands, Taiwan. The herb is a traditional anti-pyretic and hepatoprotective used in Chinese medicine. Several studies on G.

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This study describes the development of an efficient and reliable activation tagging system for the medicinal fungus Antrodia cinnamomea. For successful Agrobacterium tumefaciens-mediated transformation, different parameters were considered. The Agrobacterium concentration of 5 x 10(8) cfu ml(-1), 1mm acetosyringone, 25-d-old mycelia at 0.

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Synopsis of recent research by authors named "Dinesh Chandra Agrawal"

  • - Dinesh Chandra Agrawal's research primarily focuses on the therapeutic potential of natural compounds and the in vitro propagation of various medicinal plants, with a particular emphasis on traditional Chinese medicine.
  • - His studies, such as those involving Andrographolide, demonstrate its efficacy in relieving pain and its effects on local angiogenesis, while research on Sacha inchi explores its nutritional comparisons to other seeds and nuts, highlighting the underutilized residues from oil extraction.
  • - Agrawal also investigates the influence of environmental factors, like LED light spectra, on the growth and metabolic profiles of medicinal plants, contributing to the understanding of optimal cultivation conditions for valuable herbal resources.