Publications by authors named "Didik Pramono"

Endogenous retroviruses (ERVs) are remnants of ancestral viral infections in germ cells that constitute a substantial proportion of the mammalian genome and are assumed to provide molecular fossil records of ancient infections. Analysis of these sequences may reveal the mechanisms of virus-host co-evolution, viral endogenization, and extinction. Chimpanzee endogenous retrovirus 1 (CERV1), a gamma retrovirus, is estimated to have circulated within primates for ~10 million years, although it is now apparently extinct.

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Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections in vertebrate genomes and are inherited by offspring. ERVs can produce pathogenic viruses through gene mutations or recombination. ERVs in domestic cats (ERV-DCs) generate feline leukemia virus subgroup D (FeLV-D) through viral recombination.

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Endogenous retroviruses (ERVs) are remnants of ancestral viruses in the host genome. The present study identified the expression of a defective retroviral env gene belonging to the ERV group V member Env (EnvV) in Felis catus (EnvV-Fca). EnV-Fca was specifically detected in the placental trophoblast syncytiotrophobic layer and expressed as a secreted protein in cultured cells.

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Article Synopsis
  • Endogenous retroviruses (ERVs) are remnants of ancestral viral infections that can offer animals resistance to diseases, while feline leukemia virus (FeLV) has both exogenous and endogenous forms categorized into various subgroups.
  • The defective envelope gene of endogenous FeLV (enFeLV) may act as a co-factor in FeLV subgroup T infections, and research suggests enFeLV-derived proteins could possess antiviral properties that protect against viral transmission in domestic cats.
  • Studies showed that soluble truncated Env proteins from enFeLV effectively inhibit infections not only from enFeLV and FeLV-B but also from other retroviruses, potentially offering insights into enhancing host immunity and controlling viral spread.
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Article Synopsis
  • - Feline leukemia virus (FeLV) is a harmful virus that can lead to serious blood-related diseases in cats, with different subgroups classified based on how they interact with receptors in the host.
  • - This study studied how FeLV can recombine with endogenous retroviruses in domestic cats, finding significant genetic changes and noting the occurrence of both FeLV-D and FeLV-B in affected cats, particularly linked to cases of lymphoma and leukemia.
  • - Researchers discovered that two cats used different receptors for FeLV-B, suggesting the complexity of viral interactions and transmission, and identified a new recombinant virus (XR-FeLV) that could affect pathogenic traits in cats.
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Flying foxes belonging to the genus Pteropus are known to be reservoirs of zoonotic viruses. In this study, we describe the isolation of Pteropine orthoreovirus (PRV) from rectal swab samples of Pteropus vampyrus in Indonesia. PRV is an emerging zoonotic respiratory virus that can be transmitted from bats to humans.

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Flying foxes are important in the maintenance of forests and diversity. However, knowledge of their behavioral ecology, especially of movement and foraging patterns, which are essential for conservation and management of their populations, are not well known. Therefore, movement behavior of two individuals of Pteropus vampyrus were examined using an Argos telemetry system, and foraging pattern of Pteropus spp.

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Flying foxes, the genus Pteropus, are considered viral reservoirs. Their colonial nature and long flight capability enhance their ability to spread viruses quickly. To understand how the viral transmission occurs between flying foxes and other animals, we investigated daytime behavior of the large flying fox (Pteropus vampyrus) in the Leuweung Sancang conservation area, Indonesia, by using instantaneous scan sampling and all-occurrence focal sampling.

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