Publications by authors named "Dhruv Jayeshkumar Shah"
Introduction: RNA interference (RNAi) therapy represents an evolving advancement in the management of dyslipidemia. One prominent form of RNAi therapy is small interfering RNA (siRNA), which has emerged as a promising therapeutic strategy. This study aims to critically analyze the efficacy and safety of siRNA in the treatment of dyslipidemia.
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- - The Nipah virus, first discovered in Malaysia in 1998, has caused 25 outbreaks in South Asia, leading to 429 cases and 307 deaths, with no approved treatments available.
- - A systematic review analyzed 12 studies on Nipah virus cases, highlighting common symptoms like fever, myalgia, and respiratory distress, with a mortality rate of 73.9%.
- - Early diagnosis and treatment are essential to mitigate the severe impacts of the Nipah virus, as the most common diagnostic method is RT-PCR and transmission primarily occurs through direct contact with infected individuals.
Commonly recommended drugs for adults and children include proton pump inhibitors (PPIs), proven effective for treating peptic diseases like stomach ulcers, GERD, and Helicobacter pylori infections in children over 1-year-old. Yet, prolonged PPI use carries higher risks of adverse reactions, prompting this study's analysis. We have performed a systematic review of 30 articles, which include a total of 762 505 pediatric patients.
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- * A systematic review of 11 studies found that common MVD symptoms included fever, vomiting, and diarrhea, with a notable mortality rate of 57.1%.
- * Contact and zoonotic transmission were the primary infection routes, emphasizing the urgency for early diagnosis and treatment to prevent severe outcomes.