Potential Neurologic Manifestations of COVID-19 Infection in Neonates.

In contrast to adults, neonates and infants with coronavirus disease 2019 (COVID-19) infection have milder symptoms and are less likely to require hospitalization. However, some neonates with COVID-19 can present with significant symptoms. Recent evidence suggests that neurologic manifestations of neonatal COVID-19 infection may be higher than initially thought.

Epiploic appendagitis: Not so unusual cause of paediatric abdominal pain.

Paediatric abdominal pain continues to pose a diagnostic challenge in the acute hospital care setting. We describe an eleven-year-old boy who presented to the emergency department with acute-onset, sharp abdominal pain localised to right lower quadrant. Abdominal imaging was diagnostic for epiploic appendagitis (EA), with pathognomonic 'ring sign' and 'central dot' visualised on the axial computed tomography images.

Use of Albumin in the NICU: An Evidence-based Review.

Albumin is the most abundant protein in human blood with distinctive functions throughout the human body. Low albumin levels are a predictor of mortality as well as disease outcome in children and adults. However, the clinical significance of hypoalbuminemia and the role of albumin infusions in NICUs remain unclear and controversial.

Neurodevelopmental outcomes of singleton large for gestational age infants <29 weeks' gestation: a retrospective cohort study.

Objective: To compare neurodevelopmental outcomes of large and appropriate for gestational age (LGA, AGA) infants <29 weeks' gestation at 18-24 months of corrected age.

Study Design: Retrospective cohort study using the Canadian Neonatal Network and Canadian Neonatal Follow-Up Network databases. Primary outcome was a composite of death or significant neurodevelopmental impairment (NDI), defined as severe cerebral palsy, Bayley III cognitive, language and motor scores of <70, need for hearing aids or cochlear implant and bilateral visual impairment.

Growth Patterns in Small for Gestational Age Babies and Correlation with Insulin-like Growth Factor-1 Levels.

Objective: Correlation of catch-up growth and Insulin-like Growth Factor -1 levels (IGF-I) in SGA babies.

Methods: 50 Full-term Small for Gestational Age children aged 12-18 months were analyzed for Catch-up growth (gain in weight and/or length, Standard Deviation Score/SDS >0.67).

Posterior reversible encephalopathy syndrome in a child with meningitis presenting with transient visual loss and hypertension.

Posterior reversible encephalopathy syndrome (PRES) is a clinico- radiological syndrome characterized clinically by headache, seizures, visual disturbances, vomiting and radiologically by predominant posterior leukoencephalopathy. The authors report an 11-y-old boy with meningitis presenting with transient hypertension and visual loss and MRI finding compatible with the diagnosis of PRES and complete reversal of symptomatology within 10 d. A wide plethora of tests carried out failed to identify the cause of transient hypertension with a probability of this being due to transient autonomic dysfunction.