A comparative assessment of orthodontically induced root resorption and alveolar bone changes in adolescent orthodontic patients undergoing Micro-Osteoperforations assisted canine retraction: A Split-Mouth randomized controlled trial.

Introduction: Micro-osteoperforation (MOP) is a minimally invasive technique aimed at accelerating orthodontic tooth movement (OTM) by stimulating localised bone remodelling. However, its impact on root resorption, alveolar bone levels, and inflammatory mediators such as interleukin-4 (IL-4) requires further investigation. This study assessed root resorption, alveolar bone changes, canine angulation, rate of retraction, and IL-4 expression associated with MOP-assisted canine retraction.