Publications by authors named "Debbie J Maurer"

Strenuous exercise in elite sports impacts the immune system, leading to high rates of upper respiratory tract infections and airway dysfunction, such as asthma and exercise-induced bronchoconstriction (EIB). Cross-country (XC) skiers and ice hockey (IH) players are particularly affected due to their training environments and sports disciplines. This systematic review (SR) evaluates immune and inflammatory responses and the risk of developing airway dysfunction in these athletes.

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Background: Patients recovering from COVID-19 often present with impaired health and persisting symptoms such as exercise intolerance ⩾3 months post-infection. Uncertainty remains about long-term recovery. We aimed to review studies examining cardiac function, macro- or microvascular function, blood biomarkers and physical activity in adult patients post-COVID-19 and highlight current knowledge gaps.

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Background: Early vascular aging (EVA) is increasingly prevalent in the general population. Exercise is important for primary cardiovascular prevention, but often insufficient due to ineffective training methods and a lack of biomarkers suitable to monitor its vascular effects. VascuFit will assess the effectiveness of non-linear periodized aerobic exercise (NLPE) in a non-athletic sedentary population to improve both established and promising biomarkers of EVA.

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Background: Haemophilus influenzae (H. influenzae), Streptococcus pneumoniae (pneumococcus) and influenza vaccines are administered in children to prevent infections caused by these pathogens. The benefits of vaccination for asthma control in children and the elicited immune response are not fully understood.

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Background: The impact of physical activity on immune response is a hot topic in exercise immunology, but studies involving asthmatic children are scarce. Our aims were to examine whether there were any differences in the level of physical activity and daily TV attendance, to assess its role on asthma control and immune responses to various immune stimulants.

Methods: Weekly physical activity and daily television attendance were obtained from questionnaires at inclusion of the PreDicta study.

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Article Synopsis
  • There's been a rise in allergic diseases globally, driven by a type 2 immune response involving various immune cells, leading to significant medical and economic impacts.
  • Biomarkers play a crucial role in precision medicine by aiding in disease classification, diagnosis, therapy targeting, and treatment evaluation, with advancements in omics technologies enhancing their identification.
  • Recent research has focused on potential biomarkers for allergic diseases like asthma and atopic dermatitis, including sputum eosinophils and serum periostin, while also considering the implications of COVID-19 on managing these conditions.
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Objective: To describe the injury and illness characteristics among participating athletes during the Lausanne 2020 Youth Olympic Winter Games (YOG 2020), 9-22 January 2020.

Methods: The daily number of athlete injuries and illnesses were recorded (1) through the reporting of all National Olympic Committee (NOC) medical teams and (2) in the polyclinic and medical venues by the Lausanne 2020 medical staff.

Results: In total, 1783 athletes from 79 NOCs were observed.

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Article Synopsis
  • * Key findings highlight the importance of genetic, epigenetic, and environmental factors, as well as the significance of understanding molecular and immune mechanisms for developing new therapies.
  • * The review also addresses challenges in asthma management prompted by recent pandemics, focusing on how asthma interacts with COVID-19 and its implications for patient care.
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