Skull bone erosion in a silent atypical meningioma: A case report and literature review.

Introduction And Importance: Meningiomas are the most common primary tumors of the central nervous system. Atypical meningiomas, classified as World Health Organization (WHO) grade II, are relatively rare, accounting for 5-7 % of cases, and are known for their aggressive behaviour, including higher recurrence rates and potential brain invasion. Early detection and intervention are crucial, even in asymptomatic patients.

Comparative Effectiveness of Bariatric Surgery Versus GLP-1 Receptor Agonists in Reducing the Risk of New-Onset of NASH: A Retrospective Multinational Cohort Study From North America and Europe.

Background: Nonalcoholic steatohepatitis (NASH) is a severe form of nonalcoholic fatty liver disease (NAFLD) that can progress to cirrhosis and hepatocellular carcinoma (HCC). Obesity is a major risk factor for NASH, and metabolic interventions such as bariatric surgery (BS) and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been explored for their impact on liver-related outcomes. This study evaluates the comparative effectiveness of BS and GLP-1 RAs in reducing the incidence of new-onset NASH and related hepatic complications.

Diagnosing late-onset PKU in the shadow of refractory seizures.

Phenylketonuria (PKU), a rare autosomal recessive metabolic disorder, often presents with severe neurological complications if untreated, but late diagnosis can mimic other conditions such as Febrile Infection-Related Epilepsy Syndrome (FIRES). This report discusses a 10-year-old male initially misdiagnosed with FIRES, whose refractory seizures and encephalopathy prompted further genetic investigation. Whole-exome sequencing revealed compound heterozygous mutations in the PAH gene, confirming late-diagnosed PKU.

Efficacy and safety of preoperative embolization in surgical treatment of brain arteriovenous malformations: a multicentre study with propensity score matching.

Background: Brain arteriovenous malformations (AVMs) are abnormal connections between feeding arteries and draining veins, associated with significant risks of haemorrhage, seizures and other neurological deficits. Preoperative embolization is commonly used as an adjunct to microsurgical resection, with the aim of reducing intraoperative complications and improving outcomes. However, the efficacy and safety of this approach remain controversial.

Behçet's disease and factor V Leiden: A thrombogenic synergy causing budd-chiari syndrome.

Behçet's Disease (BD) is a multisystem inflammatory disorder that can lead to severe vascular complications, including Budd-Chiari Syndrome (BCS), a rare but life-threatening condition characterized by hepatic vein obstruction. The co-occurrence of BD and inherited thrombophilia, such as Factor V Leiden mutation, significantly increases the risk of thrombosis, complicating the clinical management of affected individuals. In this case, a 16-year-old female initially presented with nonspecific symptoms of generalized fatigue and bone pain, which later progressed to abdominal distension and significant hepatosplenomegaly.

Mixed connective tissue disease: A case of aggressive progression and multisystem involvement.

Mixed connective tissue disease (MCTD) is a rare autoimmune syndrome characterized by overlapping features of systemic sclerosis, systemic lupus erythematosus (SLE), and polymyositis, first described by Sharp et al. in 1972. This case report discusses a 38-year-old female who presented with symptoms indicative of these overlapping conditions, including sclerodactyly, Raynaud's phenomenon, and muscle weakness, confirmed by laboratory findings and imaging.

Focal necrosis of the falciform ligament as a rare cause of abdominal pain: A case report.

The falciform ligament, a peritoneal fold that anatomically separates the right and left lobes of the liver, may infrequently be a cause of patients' complaints. In very rare instances, fatty appendages of the falciform ligament may undergo torsion, resulting in fat infarction. Despite its rarity, falciform ligament pathologies often mimic common abdominal issues, leading to misdiagnosis.